Twins vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 6:13 a.m.

MLB action on Saturday includes the Minnesota Twins facing the Kansas City Royals.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Twins vs Royals Game Info

• Minnesota Twins (62-79) vs. Kansas City Royals (72-69)
• Date: Saturday, September 6, 2025
• Time: 7:15 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: FOX

Twins vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-116) | KC: (-102)
• Spread: MIN: -1.5 (+140) | KC: +1.5 (-170)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Twins vs Royals Probable Starting Pitchers

Probable Pitchers: Joe Ryan (Twins) - 13-7, 3.08 ERA vs Stephen Kolek (Royals) - 4-5, 3.99 ERA

The Twins will give the nod to Joe Ryan (13-7) versus the Royals and Stephen Kolek (4-5). Ryan and his team are 12-13-0 ATS this season when he starts. When Ryan starts a game and his team is the favorite on the moneyline, they have a record of 11-9. The Royals have gone 10-5-0 against the spread when Kolek starts. The Royals are 3-5 in Kolek's eight starts this season that they were the moneyline underdog.

Twins vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.8%)

Twins vs Royals Moneyline

• Minnesota is a -116 favorite on the moneyline, while Kansas City is a -102 underdog at home.

Twins vs Royals Spread

• The Royals are at +1.5 on the runline against the Twins. The Royals are -170 to cover the spread, and the Twins are +140.

Twins vs Royals Over/Under

• The over/under for the Twins versus Royals game on Sept. 6 has been set at 8.5, with -100 odds on the over and -122 odds on the under.

Bet on Minnesota Twins vs. Kansas City Royals on FanDuel today!

Twins vs Royals Betting Trends

• The Twins have been favorites in 81 games this season and have come away with the win 39 times (48.1%) in those contests.
• Minnesota has a record of 34-34 when favored by -116 or more this year.
• The Twins' games have gone over the total in 64 of their 136 opportunities.
• The Twins are 66-70-0 against the spread in their 136 games that had a posted line this season.
• The Royals have won 36 of the 78 games they were listed as the moneyline underdog this season (46.2%).
• Kansas City has a 27-40 record (winning 40.3% of its games) when playing as a moneyline underdog of -102 or longer.
• The Royals have had an over/under set by bookmakers 139 times, and have combined with opponents to go over the total in 58 of those games (58-79-2).
• The Royals have put together a 69-70-0 record against the spread this season.

Twins Player Leaders

• Byron Buxton leads Minnesota in total hits (112) this season while batting .271 with 53 extra-base hits. He has an on-base percentage of .330 and a slugging percentage of .553.
• Among qualifying batters in the majors, his batting average ranks 39th, his on-base percentage ranks 76th, and he is sixth in slugging.
• Trevor Larnach has hit 16 homers this season while driving in 56 runs. He's batting .258 this season and slugging .413 with an on-base percentage of .329.
• Among qualifiers, he is 81st in batting average, 80th in on-base percentage and 93rd in slugging percentage.
• Larnach takes a seven-game streak with at least one hit into this matchup. During his last 10 outings he is hitting .432 with two doubles, three walks and five RBIs.
• Brooks Lee has 102 hits this season and has a slash line of .243/.292/.381.
• Ryan Jeffers has 101 hits this season and a team-best OBP of .353.

Royals Player Leaders

• Bobby Witt Jr. has 160 hits with a .503 slugging percentage, both team-best numbers for the Royals. He's batting .294 and with an on-base percentage of .352.
• He ranks 11th in batting average, 39th in on-base percentage and 17th in slugging percentage among all qualified hitters in MLB.
• Maikel Garcia has a .357 on-base percentage to lead his team. He has a batting average of .294 while slugging .472.
• Including all qualifying hitters, he is 11th in batting average, 26th in on-base percentage and 38th in slugging percentage.
• Vinnie Pasquantino has 23 doubles, a triple, 29 home runs and 43 walks while hitting .260.
• Salvador Perez is hitting .238 with 33 doubles, 24 home runs and 23 walks.

Twins vs Royals Head to Head

• 9/5/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/10/2025: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2025: 9-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/25/2025: 2-1 KC (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/24/2025: 5-4 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/23/2025: 3-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2025: 3-2 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/9/2025: 4-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/8/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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