Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 7:14 a.m.

The Friday slate in MLB includes a matchup between the Los Angeles Dodgers and the San Francisco Giants.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (86-67) vs. San Francisco Giants (76-77)
• Date: Friday, September 19, 2025
• Time: 10:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: Apple TV+

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-168) | SF: (+142)
• Spread: LAD: -1.5 (+125) | SF: +1.5 (-150)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Clayton Kershaw (Dodgers) - 10-2, 3.53 ERA vs Robbie Ray (Giants) - 11-7, 3.50 ERA

This contest's pitching matchup is set, as the Dodgers will send Clayton Kershaw (10-2) to the mound, while Robbie Ray (11-7) will take the ball for the Giants. Kershaw and his team have a record of 10-10-0 against the spread when he starts. Kershaw's team has won 70.6% of his starts when they are favored on the moneyline (12-5). The Giants have a 19-11-0 record against the spread in Ray's starts. The Giants have been the moneyline underdog in nine of Ray's starts this season, and they went 6-3 in those games.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (60.2%)

Dodgers vs Giants Moneyline

• San Francisco is the underdog, +142 on the moneyline, while Los Angeles is a -168 favorite at home.

Dodgers vs Giants Spread

• The Dodgers are favored by 1.5 runs at home versus the Giants. The Dodgers are +125 to cover the spread, while the Giants are -150.

Dodgers vs Giants Over/Under

• The over/under for Dodgers-Giants on Sept. 19 is 8.5. The over is -104, and the under is -118.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been victorious in 76, or 56.7%, of the 134 contests they have been chosen as favorites in this season.
• Los Angeles has a record of 45-32 when favored by -168 or more this year.
• The Dodgers' games have gone over the total in 72 of their 151 opportunities.
• The Dodgers are 64-87-0 against the spread in their 151 games with a line set by sportsbooks this season.
• The Giants have won 27 of the 61 games they were the underdog on the moneyline this season (44.3%).
• San Francisco has gone 1-9 when it has played as a moneyline underdog with odds of +142 or longer (10%).
• The Giants have played in 152 games with an over/under set, and have combined with opponents to go over the total 72 times (72-72-8).
• The Giants have covered 47.4% of their games this season, going 72-80-0 against the spread.

Dodgers Player Leaders

• Shohei Ohtani has 164 hits and an OBP of .395 to go with a slugging percentage of .617. All three of those stats are tops among Los Angeles hitters this season. He has a .283 batting average, as well.
• Among all qualifying batters in baseball, he ranks 20th in batting average, second in on-base percentage, and second in slugging.
• Ohtani has recorded a base hit in six straight games. In his last 10 outings he is batting .342 with four doubles, three home runs, nine walks and five RBIs.
• Mookie Betts has 22 doubles, two triples, 19 home runs and 58 walks. He's batting .260 and slugging .409 with an on-base percentage of .328.
• Among all qualified hitters, he is 65th in batting average, 74th in on-base percentage and 89th in slugging percentage.
• Freddie Freeman has collected 156 base hits, an OBP of .365 and a slugging percentage of .495 this season.
• Freeman enters this game with two games in a row with at least one hit. During his last five outings he is batting .333 with a double, a home run, two walks and three RBIs.
• Andy Pages has been key for Los Angeles with 151 hits, an OBP of .318 plus a slugging percentage of .463.

Giants Player Leaders

• Rafael Devers has put up a team-high OBP (.372), and paces the Giants in hits (145). He's batting .253 and slugging.
• Including all the qualifying hitters in the big leagues, his batting average ranks 84th, his on-base percentage ranks ninth, and he is 40th in slugging.
• Jung Hoo Lee has 30 doubles, 11 triples, eight home runs and 47 walks while batting .261. He's slugging .403 with an on-base percentage of .325.
• He is currently 59th in batting average, 80th in on-base percentage and 97th in slugging percentage among all qualified batters.
• Willy Adames is batting .226 with 20 doubles, two triples, 28 home runs and 75 walks.
• Matt Chapman is batting .234 with 20 doubles, two triples, 21 home runs and 68 walks.

Dodgers vs Giants Head to Head

• 9/18/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/14/2025: 10-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/13/2025: 13-7 LAD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/12/2025: 5-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!