Yankees vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 4:15 a.m.

Wednesday's slate in the MLB includes a matchup between the New York Yankees and the Minnesota Twins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Yankees vs Twins Game Info

• New York Yankees (84-67) vs. Minnesota Twins (66-85)
• Date: Wednesday, September 17, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and Amazon Prime Video

Yankees vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-176) | MIN: (+148)
• Spread: NYY: -1.5 (-108) | MIN: +1.5 (-111)
• Total: 9 -- Over: (-110) | Under: (-110)

Yankees vs Twins Probable Starting Pitchers

Probable Pitchers: Luis Gil (Yankees) - 4-1, 2.83 ERA vs Taj Bradley (Twins) - 6-7, 4.88 ERA

This contest's pitching matchup is set, as the Yankees will send Luis Gil (4-1) to the mound, while Taj Bradley (6-7) will answer the bell for the Twins. Gil and his team are 4-4-0 ATS this season when he starts. Gil's team has won 62.5% of his starts when they are favored on the moneyline (5-3). The Twins have gone 11-14-0 ATS in Bradley's 25 starts with a set spread. The Twins are 5-8 in Bradley's 13 starts this season that they were the underdog on the moneyline.

Yankees vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (58.3%)

Yankees vs Twins Moneyline

• Looking at the moneyline for Twins-Yankees, Minnesota is the underdog at +148, and New York is -176 playing on the road.

Yankees vs Twins Spread

• The Yankees are favored by 1.5 runs on the road versus the Twins. The Yankees are -108 to cover the spread, while the Twins are -111.

Yankees vs Twins Over/Under

• Yankees versus Twins, on Sept. 17, has an over/under of 9, with the over being -110 and the under -110.

Bet on New York Yankees vs. Minnesota Twins on FanDuel today!

Yankees vs Twins Betting Trends

• The Yankees have been victorious in 75, or 59.1%, of the 127 contests they have been chosen as favorites in this season.
• This season New York has been victorious 27 times in 41 chances when named as a favorite of at least -176 on the moneyline.
• The Yankees and their opponents have gone over the total this season in 73 of their 149 opportunities.
• In 149 games with a line this season, the Yankees have a mark of 68-81-0 against the spread.
• The Twins have won 22 of the 57 games they were the moneyline underdog this season (38.6%).
• Minnesota has a 5-8 record (winning only 38.5% of its games) when playing as a moneyline underdog of +148 or longer.
• The Twins have played in 146 games with an over/under set, and have combined with their opponents to go over the total 70 times (70-69-7).
• The Twins have gone 71-75-0 against the spread this season.

Yankees Player Leaders

• Aaron Judge leads New York in OBP (.451), slugging percentage (.676) and total hits (164) this season. He has a .326 batting average.
• Among qualified hitters, he ranks first in batting average, his on-base percentage ranks first, and he is first in slugging.
• Cody Bellinger is batting .273 with 25 doubles, five triples, 28 home runs and 48 walks, while slugging .490 with an on-base percentage of .328.
• His batting average is 35th among qualified players, his on-base percentage 75th, and his slugging percentage 25th.
• Trent Grisham has collected 109 base hits, an OBP of .348 and a slugging percentage of .466 this season.
• Jazz Chisholm has been key for New York with 104 hits, an OBP of .335 plus a slugging percentage of .482.

Twins Player Leaders

• Byron Buxton has racked up 121 hits with a .335 on-base percentage and a .553 slugging percentage, all club-highs for the Twins. He's batting .271.
• Including all the qualifying players in MLB, his batting average ranks 37th, his on-base percentage ranks 60th, and he is fifth in slugging.
• Trevor Larnach leads his team with a .411 slugging percentage. He has a batting average of .254 with an on-base percentage of .328.
• He is currently 84th in batting average, 75th in on-base percentage and 89th in slugging percentage among all qualified batters.
• Brooks Lee has 15 doubles, a triple, 15 home runs and 30 walks while hitting .238.
• Kody Clemens is hitting .214 with 11 doubles, three triples, 19 home runs and 28 walks.

Yankees vs Twins Head to Head

• 9/16/2025: 10-9 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/15/2025: 7-0 MIN (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 8/12/2025: 9-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 8/11/2025: 6-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/6/2024: 8-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/5/2024: 9-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/4/2024: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/16/2024: 5-0 NYY (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/15/2024: 4-0 NYY (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/14/2024: 5-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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