Marlins vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 6:12 a.m.

The Wednesday schedule in MLB includes a matchup between the Miami Marlins and the Colorado Rockies.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Marlins vs Rockies Game Info

• Miami Marlins (71-80) vs. Colorado Rockies (41-110)
• Date: Wednesday, September 17, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSFL

Marlins vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-164) | COL: (+138)
• Spread: MIA: -1.5 (-110) | COL: +1.5 (-110)
• Total: 10.5 -- Over: (-122) | Under: (-100)

Marlins vs Rockies Probable Starting Pitchers

Probable Pitchers: Ryan Weathers (Marlins) - 2-1, 2.73 ERA vs McCade Brown (Rockies) - 0-4, 9.88 ERA

This contest's pitching matchup is set, as the Marlins will send Ryan Weathers (2-1) to the mound, while McCade Brown (0-4) will take the ball for the Rockies. Weathers' team is 4-2-0 against the spread this season in his starts. Weathers' team won his only start as a favorite this season. The Rockies are 1-3-0 against the spread when Brown starts. The Rockies were named the moneyline underdog for four Brown starts this season -- they lost every game.

Marlins vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (60%)

Marlins vs Rockies Moneyline

• Looking at the moneyline for Rockies-Marlins, Colorado is the underdog at +138, and Miami is -164 playing on the road.

Marlins vs Rockies Spread

• The Marlins are at the Rockies and are favored by 1.5 runs on the spread. The Marlins are -110 to cover the runline, with the Rockies being -110.

Marlins vs Rockies Over/Under

• A total of 10.5 runs has been set for the Marlins-Rockies game on Sept. 17, with the over available at -122 and the under at -100.

Bet on Miami Marlins vs. Colorado Rockies on FanDuel today!

Marlins vs Rockies Betting Trends

• The Marlins have been victorious in 11, or 42.3%, of the 26 contests they have been chosen as favorites in this season.
• Miami has been listed as a favorite of -164 or more on two occasions this season and lost both games.
• Contests with the Marlins have gone over the total set by oddsmakers in 73 of 147 chances this season.
• In 147 games with a line this season, the Marlins have a mark of 83-64-0 against the spread.
• The Rockies have a 37-106 record in games they were listed as the moneyline underdog (winning 25.9% of those games).
• Colorado has a 30-91 record (winning just 24.8% of its games) when playing as a moneyline underdog of +138 or longer.
• The Rockies have played in 147 games with a set over/under, and have combined with their opponents to go over the total 64 times (64-78-5).
• The Rockies have a 59-88-0 record ATS this season (covering 40.1% of the time).

Marlins Player Leaders

• Otto Lopez is hitting .248 with 18 doubles, 14 home runs and 44 walks. He has an on-base percentage of .311 and a slugging percentage of .369.
• Among all qualified hitters in MLB, his batting average ranks 95th, his on-base percentage ranks 106th, and he is 133rd in slugging.
• Xavier Edwards has a slash line of .280/.339/.353 this season and a team-best OPS of .692.
• His batting average is 23rd among qualified players, his on-base percentage 53rd, and his slugging percentage 142nd.
• Agustin Ramirez leads Miami with 114 hits. He is batting .230 this season and 50 of his hits have gone for extra bases.
• Ramirez takes a seven-game hitting streak into this matchup. During his last 10 outings he is batting .263 with a double, a home run, three walks and three RBIs.
• Eric Wagaman has been key for Miami with 113 hits, an OBP of .299 plus a slugging percentage of .384.
• Wagaman heads into this game on a five-game hitting streak. In his last five games he is batting .556 with two doubles and four RBIs.

Rockies Player Leaders

• Hunter Goodman has racked up 137 hits with a .524 slugging percentage, both team-high figures for the Rockies. He's batting .276 and with an on-base percentage of .321.
• He ranks 31st in batting average, 92nd in on-base percentage and 10th in slugging percentage among all qualified batters in the majors.
• Mickey Moniak has 17 doubles, eight triples, 22 home runs and 21 walks while batting .270. He's slugging .515 with an on-base percentage of .307.
• Jordan Beck has a team-high .330 on-base percentage.
• Tyler Freeman is hitting .279 with 19 doubles, two triples, two home runs and 34 walks.

Marlins vs Rockies Head to Head

• 9/16/2025: 6-5 MIA (Favorite: Marlins, Spread: -1.5, Total: 10, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/4/2025: 3-2 COL (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/3/2025: 3-2 COL (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/2/2025: 6-4 COL (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/29/2024: 12-8 MIA (Favorite: Rockies, Spread: -1.5, Total: 11.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/28/2024: 8-2 COL (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/27/2024: 9-8 MIA (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/26/2024: 3-2 COL (Favorite: Rockies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/2/2024: 5-4 MIA (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/1/2024: 4-1 MIA (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)

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