Rangers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 4:17 a.m.

In MLB action on Wednesday, the Texas Rangers take on the Houston Astros.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Rangers vs Astros Game Info

• Texas Rangers (79-73) vs. Houston Astros (83-69)
• Date: Wednesday, September 17, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and RSN

Rangers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TEX: (-126) | HOU: (+108)
• Spread: TEX: -1.5 (+134) | HOU: +1.5 (-162)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Rangers vs Astros Probable Starting Pitchers

Probable Pitchers: Jacob deGrom (Rangers) - 12-7, 2.82 ERA vs Cristian Javier (Astros) - 1-3, 4.78 ERA

The probable starters are Jacob deGrom (12-7) for the Rangers and Cristian Javier (1-3) for the Astros. When deGrom starts, his team is 12-16-0 against the spread this season. deGrom's team has a record of 14-10 this season when he starts and they are the favorite on the moneyline. The Astros have gone 2-4-0 ATS in Javier's six starts with a set spread. The Astros have been the moneyline underdog in four of Javier's starts this season, and they went 2-2 in those matchups.

Rangers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (51.3%)

Rangers vs Astros Moneyline

• Houston is a +108 underdog on the moneyline, while Texas is a -126 favorite on the road.

Rangers vs Astros Spread

• The Rangers are 1.5-run road favorites on the runline against the Astros. The Rangers are +134 to cover, and the Astros are -162.

Rangers vs Astros Over/Under

• An over/under of 7.5 has been set for Rangers-Astros on Sept. 17, with the over being -120 and the under -102.

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Rangers vs Astros Betting Trends

• The Rangers have been favorites in 71 games this season and have come away with the win 45 times (63.4%) in those contests.
• This year Texas has won 33 of 50 games when listed as at least -126 on the moneyline.
• The Rangers and their opponents have gone over in 68 of their 151 games with a total set by sportsbooks this season.
• In 151 games with a line this season, the Rangers have a mark of 82-69-0 against the spread.
• The Astros are 31-23 in games they were listed as the moneyline underdog (winning 57.4% of those games).
• When it has played as a moneyline underdog with odds of +108 or longer, Houston has a record of 19-15 (55.9%).
• The Astros have combined with opponents to go over the total 69 times this season for a 69-78-4 record against the over/under.
• The Astros have collected a 76-75-0 record against the spread this season.

Rangers Player Leaders

• Wyatt Langford leads Texas with 117 hits and an OBP of .343 this season. He has a .243 batting average and a slugging percentage of .429.
• Among qualified hitters in MLB, his batting average ranks 104th, his on-base percentage ranks 47th, and he is 76th in slugging.
• Josh Smith leads Texas in slugging percentage (.370) thanks to 34 extra-base hits. He's batting .257 with an on-base percentage of .341.
• Among qualifying hitters, his batting average places him 77th, his on-base percentage 51st, and his slugging percentage 131st.
• Smith has picked up a hit in two games in a row. In his last five games he is batting .316 with a double, two walks and an RBI.
• Adolis Garcia has 113 hits this season and has a slash line of .233/.275/.402.
• Josh Jung has been key for Texas with 111 hits, an OBP of .294 plus a slugging percentage of .395.
• Jung heads into this matchup on a two-game hitting streak. During his last five outings he is hitting .250 with two doubles, a home run, a walk and four RBIs.

Astros Player Leaders

• Jose Altuve has put up a slugging percentage of .440, a team-high for the Astros. He's batting .263 with an on-base percentage of .325.
• Including all qualified hitters, he is 54th in batting average, while his on-base percentage is 83rd and he is 65th in slugging.
• Jeremy Pena has 146 hits with a .363 on-base percentage to lead his team in both. He has a batting average of .304 while slugging .466.
• Including all qualified hitters, his batting average puts him sixth, his on-base percentage is 16th, and he is 43rd in slugging.
• Yainer Diaz is batting .257 with 23 doubles, a triple, 19 home runs and 20 walks.
• Christian Walker is hitting .236 with 23 doubles, a triple, 23 home runs and 40 walks.

Rangers vs Astros Head to Head

• 9/16/2025: 6-5 HOU (Favorite: Rangers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/15/2025: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/7/2025: 4-2 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/6/2025: 11-0 HOU (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/5/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/13/2025: 5-1 TEX (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/11/2025: 7-3 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/18/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/17/2025: 5-1 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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