Phillies vs Mets Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 6:12 a.m.

The MLB's Wednesday schedule includes the Philadelphia Phillies facing the New York Mets.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Mets Game Info

• Philadelphia Phillies (85-60) vs. New York Mets (76-69)
• Date: Wednesday, September 10, 2025
• Time: 6:45 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and SNY

Phillies vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-172) | NYM: (+144)
• Spread: PHI: -1.5 (+125) | NYM: +1.5 (-150)
• Total: 8 -- Over: (-105) | Under: (-115)

Phillies vs Mets Probable Starting Pitchers

Probable Pitchers: Cristopher Sanchez (Phillies) - 12-5, 2.60 ERA vs Clay Holmes (Mets) - 11-7, 3.61 ERA

The Phillies will give the nod to Cristopher Sanchez (12-5) versus the Mets and Clay Holmes (11-7). Sanchez and his team have a record of 16-12-0 against the spread when he starts. When Sanchez starts a game and his team is the favorite on the moneyline, they have a record of 19-6. The Mets have gone 11-14-0 against the spread when Holmes starts. The Mets are 2-3 in Holmes' five starts this season that they were the moneyline underdog.

Phillies vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (60.6%)

Phillies vs Mets Moneyline

• Looking at the moneyline for Phillies-Mets, Philadelphia is the favorite at -172, and New York is +144 playing on the road.

Phillies vs Mets Spread

• The Phillies are hosting the Mets and are favored by 1.5 runs on the spread. The Phillies are +125 to cover the runline, with the Mets being -150.

Phillies vs Mets Over/Under

• Phillies versus Mets on Sept. 10 has an over/under of 8 runs, with the odds on the over -105 and the under set at -115.

Bet on Philadelphia Phillies vs. New York Mets on FanDuel today!

Phillies vs Mets Betting Trends

• The Phillies have won in 71, or 64.5%, of the 110 contests they have been named as odds-on favorites in this year.
• This year Philadelphia has won 36 of 47 games when listed as at least -172 on the moneyline.
• Contests with the Phillies have gone over the total set by oddsmakers in 54 of 138 chances this season.
• The Phillies have posted a record of 71-67-0 against the spread this season.
• The Mets have gone 15-23 in games they were the underdog on the moneyline (winning 39.5% of those games).
• New York has played in three games as a moneyline underdog with odds of +144 or longer without claiming a victory.
• The Mets have played in 138 games with a set over/under, and have combined with their opponents to go over the total 63 times (63-67-8).
• The Mets have a 65-73-0 record against the spread this season (covering 47.1% of the time).

Phillies Player Leaders

• Kyle Schwarber has 130 hits and an OBP of .364, both of which are tops among Philadelphia hitters this season. He has a .240 batting average and a slugging percentage of .562.
• Among the qualified hitters in the majors, his batting average ranks 113th, his on-base percentage ranks 17th, and he is fifth in slugging.
• Bryce Harper has 30 doubles, 24 home runs and 58 walks. He's batting .263 and slugging .491 with an on-base percentage of .352.
• His batting average ranks 60th among qualified players, his on-base percentage 34th, and his slugging percentage 24th.
• Bryson Stott is batting .255 with a .381 slugging percentage and 61 RBI this year.
• Stott brings a two-game hitting streak into this game. During his last five outings he is hitting .412 with a double, a home run, two walks and five RBIs.
• Nick Castellanos has been key for Philadelphia with 129 hits, an OBP of .296 plus a slugging percentage of .406.
• Castellanos has safely hit in four straight games. In his last five games he is hitting .294 with a double, a triple, two walks and four RBIs.

Mets Player Leaders

• Juan Soto has racked up a team-high OBP (.399), while leading the Mets in hits (133). He's batting .261 and slugging.
• Including all the qualifying hitters in the big leagues, his batting average is 70th, his on-base percentage ranks second, and he is 13th in slugging.
• Francisco Lindor's .454 slugging percentage leads his team. He has a batting average of .264 with an on-base percentage of .339.
• He ranks 57th in batting average, 52nd in on-base percentage and 56th in slugging percentage in the big leagues.
• Pete Alonso has 37 doubles, a triple, 33 home runs and 56 walks while batting .269.
• Brandon Nimmo is batting .263 with 27 doubles, 22 home runs and 48 walks.

Phillies vs Mets Head to Head

• 9/9/2025: 9-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/8/2025: 1-0 PHI (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/27/2025: 6-0 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/26/2025: 6-5 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/25/2025: 13-3 NYM (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/22/2025: 7-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/21/2025: 11-4 NYM (Favorite: Mets, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/20/2025: 10-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 4/23/2025: 4-3 NYM (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/22/2025: 5-1 NYM (Favorite: Phillies, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!