Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 9:12 a.m.

The Tampa Bay Rays will face the Chicago White Sox in MLB action on Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Rays vs White Sox Game Info

• Tampa Bay Rays (72-72) vs. Chicago White Sox (55-90)
• Date: Wednesday, September 10, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSSUN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-142) | CHW: (+120)
• Spread: TB: -1.5 (+116) | CHW: +1.5 (-140)
• Total: 8 -- Over: (-105) | Under: (-115)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Griffin Jax (Rays) - 1-7, 4.81 ERA vs TBA (White Sox)

The Rays will look to Griffin Jax (1-7), while the White Sox's starting pitcher has not yet been announced. Jax and his team failed to cover the spread in his only opportunity this season as a starter. Jax's team lost his only start as a favorite this season.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (69.1%)

Rays vs White Sox Moneyline

• Chicago is the underdog, +120 on the moneyline, while Tampa Bay is a -142 favorite despite being on the road.

Rays vs White Sox Spread

• The Rays are favored by 1.5 runs on the road versus the White Sox. The Rays are +116 to cover the spread, while the White Sox are -140.

Rays vs White Sox Over/Under

• The over/under for the Rays versus White Sox game on Sept. 10 has been set at 8, with -105 odds on the over and -115 odds on the under.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have been chosen as favorites in 67 games this year and have walked away with the win 39 times (58.2%) in those games.
• Tampa Bay has a record of 16-16 in contests when oddsmakers favor them by -142 or more on the moneyline.
• Contests with the Rays have gone over the total set by oddsmakers in 60 of 139 chances this season.
• The Rays have posted a record of 61-78-0 against the spread this season.
• The White Sox have a 51-86 record in games they were listed as the moneyline underdog (winning 37.2% of those games).
• Chicago has a record of 37-68 when playing as a moneyline underdog with odds of +120 or longer (35.2%).
• The White Sox have played in 140 games with a set over/under, and have combined with their opponents to go over the total 66 times (66-66-8).
• The White Sox have collected an 80-60-0 record against the spread this season (covering 57.1% of the time).

Rays Player Leaders

• Junior Caminero leads Tampa Bay in total hits (142) this season while batting .261 with 67 extra-base hits. He has an on-base percentage of .301 and a slugging percentage of .535.
• Among the qualified hitters in MLB, his batting average ranks 70th, his on-base percentage ranks 123rd, and he is 11th in slugging.
• Caminero has hit safely in two games in a row. In his last five games he is hitting .200 with a double, a home run and an RBI.
• Yandy Diaz has a slash line of .290/.348/.468 this season and a team-best OPS of .816.
• He is 13th in batting average, 40th in on-base percentage and 42nd in slugging in the major leagues.
• Brandon Lowe has collected 119 base hits, an OBP of .314 and a slugging percentage of .485 this season.
• Chandler Simpson has been key for Tampa Bay with 101 hits, an OBP of .320 plus a slugging percentage of .335.
• Simpson enters this matchup on a two-game hitting streak. In his last five games he is hitting .250 with an RBI.

White Sox Player Leaders

• Andrew Benintendi has 16 doubles, two triples, 18 home runs and 37 walks while hitting .248. He's slugging .433 with an on-base percentage of .312.
• Benintendi takes a four-game hitting streak into this game. During his last five outings he is batting .294 with a double, a home run, three walks and five RBIs.
• Lenyn Sosa's 123 hits and .435 slugging percentage both pace his team. He has a batting average of .265 with an on-base percentage of .297.
• Including all qualifying hitters, he is 54th in batting average, 128th in on-base percentage and 76th in slugging percentage.
• Chase Meidroth is batting .265 with 15 doubles, four home runs and 41 walks.
• Mike Tauchman has 15 doubles, a triple, eight home runs and 41 walks while batting .270.

Rays vs White Sox Head to Head

• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/30/2023: 12-9 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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