Mets vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 4:16 a.m.

On Wednesday in MLB, the New York Mets are playing the San Diego Padres.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Mets vs Padres Game Info

• New York Mets (78-73) vs. San Diego Padres (82-69)
• Date: Wednesday, September 17, 2025
• Time: 7:10 p.m. ET
• Venue: Citi Field -- Queens, New York
• Coverage: SNY and SDPA

Mets vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-108) | SD: (-108)
• Spread: NYM: +1.5 (-184) | SD: -1.5 (+152)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Mets vs Padres Probable Starting Pitchers

Probable Pitchers: David Peterson (Mets) - 9-5, 3.77 ERA vs Nick Pivetta (Padres) - 13-5, 2.73 ERA

The Mets will give the nod to David Peterson (9-5, 3.77 ERA), who is eyeing win No. 10 on the season, and the Padres will turn to Nick Pivetta (13-5, 2.73 ERA). Peterson and his team have a record of 8-17-0 against the spread when he starts. Peterson's team is 12-7 this season when he starts and they are the moneyline favorite. The Padres have a 16-13-0 ATS record in Pivetta's 29 starts that had a set spread. The Padres are 5-3 in Pivetta's eight starts this season that they were the moneyline underdog.

Mets vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (51.2%)

Mets vs Padres Moneyline

• San Diego is the underdog, -108 on the moneyline, while New York is a -108 favorite at home.

Mets vs Padres Spread

Mets vs Padres Over/Under

• A combined run total of 7.5 has been set for Mets-Padres on Sept. 17, with the over at -118 and the under at -104.

Bet on New York Mets vs. San Diego Padres on FanDuel today!

Mets vs Padres Betting Trends

• The Mets have been victorious in 59, or 57.8%, of the 102 contests they have been chosen as favorites in this season.
• New York has a record of 60-44 in contests when oddsmakers favor them by -108 or more on the moneyline.
• The Mets and their opponents have gone over in 67 of their 144 games with a total set by sportsbooks this season.
• In 144 games with a line this season, the Mets have a mark of 67-77-0 against the spread.
• The Padres have been the moneyline underdog 63 total times this season. They've gone 30-33 in those games.
• San Diego has a record of 30-33 when it has played as a moneyline underdog with odds of -108 or longer (47.6%).
• The Padres have played in 149 games with an over/under set, and have combined with opponents to go over the total 65 times (65-81-3).
• The Padres have covered 53.7% of their games this season, going 80-69-0 ATS.

Mets Player Leaders

• Juan Soto leads New York with 140 hits and an OBP of .395 this season. He has a .262 batting average and a slugging percentage of .523.
• Among qualified hitters in baseball, he is 60th in batting average, second in on-base percentage, and 11th in slugging.
• Francisco Lindor has an OPS of .794, fueled by an OBP of .340 and a team-best slugging percentage of .454 this season. He's batting .265.
• His batting average is 47th among qualified players, his on-base percentage 52nd, and his slugging percentage 56th.
• Lindor enters this game looking to extend his five-game hit streak. In his last five games he is hitting .316 with a double, a home run, three walks and an RBI.
• Pete Alonso is batting .268 with a .515 slugging percentage and 118 RBI this year.
• Alonso brings a three-game hitting streak into this game. In his last five games he is hitting .250 with two home runs, a walk and five RBIs.
• Brandon Nimmo has been key for New York with 142 hits, an OBP of .327 plus a slugging percentage of .440.
• Nimmo heads into this matchup on a three-game hitting streak. In his last five games he is hitting .300 with a home run and three RBIs.

Padres Player Leaders

• Fernando Tatis Jr. is batting .262 with 27 doubles, two triples, 22 home runs and 86 walks. He's slugging .434 with an on-base percentage of .365.
• Including all the qualifying players in MLB, his batting average ranks 60th, his on-base percentage is 13th, and he is 72nd in slugging.
• Manny Machado has 160 hits to pace his team. He has a batting average of .276 while slugging .463 with an on-base percentage of .338.
• Including all qualifying players, he ranks 31st in batting average, 56th in on-base percentage and 46th in slugging percentage.
• Luis Arraez has accumulated a slugging percentage of .386, a team-best for the Padres.
• Ramon Laureano is hitting .286 with 25 doubles, two triples, 23 home runs and 33 walks.

Mets vs Padres Head to Head

• 9/16/2025: 8-3 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/30/2025: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/29/2025: 7-1 SD (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/28/2025: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/25/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/24/2024: 7-1 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/23/2024: 7-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/22/2024: 8-3 NYM (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/16/2024: 11-6 NYM (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2024: 5-1 NYM (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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