Marlins vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 5:19 a.m.

MLB action on Wednesday includes the Miami Marlins playing the Washington Nationals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Marlins vs Nationals Game Info

• Miami Marlins (66-79) vs. Washington Nationals (60-84)
• Date: Wednesday, September 10, 2025
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and MASN2

Marlins vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-162) | WSH: (+136)
• Spread: MIA: -1.5 (+128) | WSH: +1.5 (-154)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Marlins vs Nationals Probable Starting Pitchers

Probable Pitchers: Eury Pérez (Marlins) - 6-5, 4.66 ERA vs Jake Irvin (Nationals) - 8-11, 5.71 ERA

The Marlins will give the nod to Eury Perez (6-5, 4.66 ERA), who is eyeing win No. 7 on the season, and the Nationals will counter with Jake Irvin (8-11, 5.71 ERA). When Perez starts, his team is 8-6-0 against the spread this season. When Perez starts a game and his team is the favorite on the moneyline, they have a record of 1-4. The Nationals have a 15-13-0 record against the spread in Irvin's starts. The Nationals are 13-14 in Irvin's 27 starts this season that they were the underdog on the moneyline.

Marlins vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (61.4%)

Marlins vs Nationals Moneyline

• Looking at the moneyline for Marlins-Nationals, Miami is the favorite at -162, and Washington is +136 playing on the road.

Marlins vs Nationals Spread

• The Marlins are hosting the Nationals and are favored by 1.5 runs (+128 to cover) on the runline. Washington is -154 to cover.

Marlins vs Nationals Over/Under

• The Marlins-Nationals contest on Sept. 10 has been given an over/under of 8.5 runs. The over is set at -105 and the under at -115.

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Marlins vs Nationals Betting Trends

• The Marlins have been favorites in 23 games this season and have come away with the win eight times (34.8%) in those contests.
• Miami has been listed as a favorite of -162 or more on two occasions this season and lost both games.
• The Marlins and their opponents have gone over the total this season in 69 of their 141 opportunities.
• The Marlins have an against the spread mark of 79-62-0 in 141 games with a line this season.
• The Nationals have won 52 of the 117 games they were the underdog on the moneyline this season (44.4%).
• In games it has played as a moneyline underdog with odds of +136 or longer, Washington has a 24-33 record (winning 42.1% of its games).
• In the 138 games oddsmakers have set an over/under for the Nationals, they have combined with opponents to go over the total 74 times (74-57-7).
• The Nationals have collected a 70-68-0 record against the spread this season.

Marlins Player Leaders

• Otto Lopez is batting .249 with 18 doubles, 14 home runs and 44 walks. He has an on-base percentage of .315 while slugging .376.
• Among all qualified batters in MLB, his batting average ranks 93rd, his on-base percentage ranks 104th, and he is 129th in slugging.
• Lopez has recorded at least one hit in three straight games. In his last five games he is hitting .353 with two home runs and four RBIs.
• Xavier Edwards leads Miami in slugging percentage (.348) thanks to 27 extra-base hits. He's batting .279 with an on-base percentage of .337.
• Among all qualified hitters, he is 25th in batting average, 54th in on-base percentage and 141st in slugging percentage.
• Edwards enters this game looking to extend his two-game hit streak. During his last five outings he is batting .143 with three walks and two RBIs.
• Agustin Ramirez has 107 hits this season and has a slash line of .226/.283/.410.
• Eric Wagaman has nine home runs, 46 RBI and a batting average of .238 this season.

Nationals Player Leaders

• C.J. Abrams has 33 doubles, five triples, 17 home runs and 35 walks while hitting .268. He's slugging .451 with an on-base percentage of .331.
• He is 47th in batting average, 71st in on-base percentage and 60th in slugging percentage among all qualified hitters in the big leagues.
• Abrams brings a six-game hitting streak into this game. In his last 10 games he is hitting .289 with six doubles and three walks.
• James Wood has collected 140 hits with a .357 OBP while slugging .473. Those stats all pace his team. He also has a batting average of .260.
• He ranks 73rd in batting average, 26th in on-base percentage and 34th in slugging percentage in the big leagues.
• Luis Garcia is hitting .260 with 27 doubles, a triple, 13 home runs and 26 walks.
• Josh Bell is batting .232 with 13 doubles, a triple, 20 home runs and 54 walks.

Marlins vs Nationals Head to Head

• 9/9/2025: 7-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 9/8/2025: 15-7 WSH (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/3/2025: 10-5 WSH (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/2/2025: 5-2 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/1/2025: 2-0 WSH (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/15/2025: 3-1 MIA (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/14/2025: 4-3 MIA (Favorite: Nationals, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/13/2025: 11-9 MIA (Favorite: Nationals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/13/2025: 11-4 MIA (Favorite: Nationals, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/12/2025: 7-6 MIA (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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