Giants vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 9:12 a.m.

On Monday in MLB, the San Francisco Giants are up against the Arizona Diamondbacks.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Diamondbacks Game Info

• San Francisco Giants (72-71) vs. Arizona Diamondbacks (72-72)
• Date: Monday, September 8, 2025
• Time: 9:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: Fox Sports 1, NBCS-BA, and ARID

Giants vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-190) | ARI: (+160)
• Spread: SF: -1.5 (+118) | ARI: +1.5 (-142)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Giants vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 13-9, 3.17 ERA vs Nabil Crismatt (Diamondbacks) - 2-0, 2.14 ERA

The probable starters are Logan Webb (13-9) for the Giants and Nabil Crismatt (2-0) for the Diamondbacks. Webb and his team are 13-16-0 ATS this season when he starts. Webb's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 13-13. When Crismatt starts, the Diamondbacks have gone 2-1-0 against the spread. The Diamondbacks were named the moneyline underdog for one Crismatt start this season -- they won.

Giants vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.2%)

Giants vs Diamondbacks Moneyline

• San Francisco is the favorite, -190 on the moneyline, while Arizona is a +160 underdog on the road.

Giants vs Diamondbacks Spread

• The Giants are hosting the Diamondbacks and are favored by 1.5 runs on the spread. The Giants are +118 to cover the runline, with the Diamondbacks being -142.

Giants vs Diamondbacks Over/Under

• A total of 7.5 runs has been set for the Giants-Diamondbacks game on Sept. 8, with the over available at -112 and the under at -108.

Bet on San Francisco Giants vs. Arizona Diamondbacks on FanDuel today!

Giants vs Diamondbacks Betting Trends

• The Giants have won in 45, or 52.9%, of the 85 contests they have been named as odds-on favorites in this year.
• San Francisco has a record of 8-5 when favored by -190 or more this year.
• The Giants and their opponents have gone over in 67 of their 142 games with a total set by sportsbooks this season.
• The Giants have an against the spread record of 66-76-0 in 142 games with a line this season.
• The Diamondbacks are 28-29 in games they were the underdog on the moneyline (winning 49.1% of those games).
• Arizona has a 2-2 record (winning 50% of its games) when it has played as a moneyline underdog of +160 or longer.
• In the 140 games bookmakers have set an over/under for the Diamondbacks, they have combined with opponents to go over the total 69 times (69-65-6).
• The Diamondbacks have a 69-71-0 record against the spread this season.

Giants Player Leaders

• Rafael Devers has 141 hits and an OBP of .380, both of which lead San Francisco hitters this season. He has a .263 batting average and a slugging percentage of .492.
• Among all qualified hitters in the majors, he ranks 67th in batting average, ninth in on-base percentage, and 25th in slugging.
• Jung Hoo Lee is batting .267 with 30 doubles, 11 triples, seven home runs and 44 walks, while slugging .411 with an on-base percentage of .329.
• Among qualified hitters, he ranks 48th in batting average, 76th in on-base percentage and 89th in slugging percentage.
• Willy Adames has collected 119 base hits, an OBP of .317 and a slugging percentage of .425 this season.
• Heliot Ramos leads San Francisco with a slugging percentage of .401, fueled by 40 extra-base hits.

Diamondbacks Player Leaders

• Geraldo Perdomo has accumulated a slugging percentage of .447, a team-high for the Diamondbacks. He's batting .284 with an on-base percentage of .382.
• Including all qualified players, he is 19th in batting average, while his on-base percentage ranks seventh and he is 63rd in slugging.
• Corbin Carroll leads his team with 131 hits. He has a batting average of .259 while slugging .558 with an on-base percentage of .336.
• Including all qualified hitters, he ranks 79th in batting average, 63rd in on-base percentage and sixth in slugging percentage.
• Ketel Marte has put up a team-high .386 on-base percentage.
• Gabriel Moreno is batting .277 with 11 doubles, a triple, seven home runs and 17 walks.

Giants vs Diamondbacks Head to Head

• 7/3/2025: 7-2 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/2/2025: 6-5 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 7/1/2025: 8-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/30/2025: 4-2 ARI (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/14/2025: 8-7 ARI (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/13/2025: 10-6 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/12/2025: 2-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/25/2024: 8-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 9/24/2024: 11-0 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/23/2024: 6-3 SF (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)

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