Chiefs vs Chargers Prediction, Odds, Picks, Best Bets for NFL Week 1

The NFL schedule on Friday includes the Kansas City Chiefs taking on the Los Angeles Chargers.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Chiefs vs Chargers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Chiefs win (58.7%)

Chiefs vs Chargers Point Spread

The Chiefs are 3-point favorites against the Chargers. The Chiefs are -118 to cover the spread, while the Chargers are -104 to cover as a 3-point underdog.

Chiefs vs Chargers Over/Under

The over/under for Chiefs-Chargers on Sept. 5 is 47.5. The over is -105, and the under is -115.

Chiefs vs Chargers Moneyline

The Chiefs vs Chargers moneyline has the Chiefs as a -166 favorite, while the Chargers are a +140 underdog at home.

Chiefs vs Chargers Betting Trends

• The Chiefs had seven wins in 17 games against the spread last year.
• The Chiefs went 5-7-1 ATS as 3-point favorites or more last year.
• In 17 Kansas City games last year, seven hit the over.
• Against the spread, the Chargers were 12-4-1 last year.
• As a 3-point underdog or more, Los Angeles had one win ATS (1-1-1) last year.
• The Chargers had eight of their 17 games hit the over last year.

Check out even more in-depth Chiefs vs. Chargers analysis on FanDuel Research.

Chiefs vs Chargers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-166) | LAC: (+140)
• Spread: KC: -3 (-118) | LAC: +3 (-104)
• Total: 47.5 -- Over: (-105) | Under: (-115)

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