Yankees vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 2:12 a.m.

The Friday slate in MLB includes a matchup between the New York Yankees and the Baltimore Orioles.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Orioles Game Info

• New York Yankees (86-67) vs. Baltimore Orioles (72-81)
• Date: Friday, September 19, 2025
• Time: 7:05 p.m. ET
• Venue: Oriole Park at Camden Yards -- Baltimore, Maryland
• Coverage: MASN and YES

Yankees vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-116) | BAL: (-102)
• Spread: NYY: -1.5 (+138) | BAL: +1.5 (-166)
• Total: 9 -- Over: (-105) | Under: (-115)

Yankees vs Orioles Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 8-7, 4.44 ERA vs Trevor Rogers (Orioles) - 8-2, 1.43 ERA

The Yankees will give the ball to Will Warren (8-7, 4.44 ERA), who is eyeing win No. 9 on the season, and the Orioles will counter with Trevor Rogers (8-2, 1.43 ERA). Warren and his team have a record of 12-19-0 against the spread when he starts. Warren's team is 15-10 this season when he starts and they are the moneyline favorite. The Orioles have an 11-4-0 record against the spread in Rogers' starts. The Orioles are 6-3 in Rogers' nine starts this season that they were the underdog on the moneyline.

Yankees vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (52.9%)

Yankees vs Orioles Moneyline

• New York is a -116 favorite on the moneyline, while Baltimore is a -102 underdog at home.

Yankees vs Orioles Spread

• The Orioles are +1.5 on the run line against the Yankees. The Orioles are -166 to cover, and the Yankees are +138.

Yankees vs Orioles Over/Under

• The over/under for the Yankees versus Orioles contest on Sept. 19 has been set at 9, with -105 odds on the over and -115 odds on the under.

Bet on New York Yankees vs. Baltimore Orioles on FanDuel today!

Yankees vs Orioles Betting Trends

• The Yankees have been chosen as favorites in 129 games this year and have walked away with the win 77 times (59.7%) in those games.
• New York has a record of 75-51 when favored by -116 or more this year.
• The Yankees' games have gone over the total in 74 of their 151 opportunities.
• The Yankees have an against the spread record of 70-81-0 in 151 games with a line this season.
• The Orioles have won 45.3% of the games this season they were the moneyline underdog (39-47).
• Baltimore is 34-43 (winning 44.2% of its games) when it has played as a moneyline underdog of -102 or longer.
• The Orioles have had an over/under set by oddsmakers 150 times, and have combined with opponents to go over the total in 63 of those games (63-83-4).
• The Orioles are 72-78-0 against the spread this season.

Yankees Player Leaders

• Aaron Judge leads New York with 167 hits and an OBP of .453, plus a team-best slugging percentage of .676. He's batting .328.
• Among qualifying hitters, he ranks first in batting average, his on-base percentage ranks first, and he is first in slugging.
• Cody Bellinger is batting .273 with 25 doubles, five triples, 29 home runs and 50 walks. He's slugging .493 with an on-base percentage of .331.
• His batting average ranks 34th among qualified players, his on-base percentage 69th, and his slugging percentage 23rd.
• Trent Grisham has 111 hits this season and has a slash line of .239/.347/.475.
• Jazz Chisholm has 29 home runs, 75 RBI and a batting average of .242 this season.

Orioles Player Leaders

• Gunnar Henderson has racked up an on-base percentage of .347, a slugging percentage of .439, and has 149 hits, all club-highs for the Orioles (while batting .273).
• Including all the qualified hitters in the big leagues, his batting average ranks 34th, his on-base percentage is 41st, and he is 68th in slugging.
• Henderson brings a three-game hitting streak into this matchup. In his last five games he is batting .350 with two walks and two RBIs.
• Jackson Holliday has 21 doubles, three triples, 17 home runs and 53 walks while batting .250. He's slugging .390 with an on-base percentage of .321.
• He ranks 92nd in batting average, 90th in on-base percentage and 114th in slugging percentage in the majors.
• Jordan Westburg has nine doubles, a triple, 15 home runs and 17 walks while batting .264.
• Colton Cowser is batting .199 with 12 doubles, 15 home runs and 22 walks.

Yankees vs Orioles Head to Head

• 9/18/2025: 7-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/22/2025: 4-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 6/21/2025: 9-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/20/2025: 5-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -310, Underdog Moneyline: +250)
• 4/30/2025: 5-4 BAL (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/29/2025: 15-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/28/2025: 4-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/26/2024: 10-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/25/2024: 9-7 BAL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/24/2024: 5-3 BAL (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)

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