Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 7

Odds updated as of 5:20 a.m.

The MLB's Sunday schedule includes the Milwaukee Brewers taking on the Pittsburgh Pirates.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Pirates Game Info

• Milwaukee Brewers (88-55) vs. Pittsburgh Pirates (64-79)
• Date: Sunday, September 7, 2025
• Time: 1:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSWI

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-154) | PIT: (+130)
• Spread: MIL: -1.5 (+116) | PIT: +1.5 (-140)
• Total: 8 -- Over: (-105) | Under: (-115)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 4-2, 4.50 ERA vs Bubba Chandler (Pirates) - 2-0, 2.25 ERA

The Brewers will look to Jacob Misiorowski (4-2) versus the Pirates and Bubba Chandler (2-0). Misiorowski and his team are 7-4-0 ATS this season when he starts. When Misiorowski starts a game and his team is the favorite on the moneyline, they have a record of 2-3. Chandler's team was never a moneyline underdog a season ago in games he pitched.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (59.2%)

Brewers vs Pirates Moneyline

• Milwaukee is the favorite, -154 on the moneyline, while Pittsburgh is a +130 underdog despite being at home.

Brewers vs Pirates Spread

• The Pirates are +1.5 on the run line against the Brewers. The Pirates are -140 to cover, and the Brewers are +116.

Brewers vs Pirates Over/Under

• The over/under for the Brewers versus Pirates game on Sept. 7 has been set at 8, with -105 odds on the over and -115 odds on the under.

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Brewers vs Pirates Betting Trends

• The Brewers have won in 52, or 65.8%, of the 79 contests they have been named as odds-on favorites in this year.
• Milwaukee has a record of 20-7 when favored by -154 or more this year.
• The Brewers and their opponents have hit the over in 69 of their 140 games with a total set by oddsmakers this season.
• The Brewers are 80-60-0 against the spread in their 140 games with a line set by sportsbooks this season.
• The Pirates have gone 41-54 in games they were the underdog on the moneyline (winning 43.2% of those games).
• When it has played as a moneyline underdog with odds of +130 or longer, Pittsburgh has a record of 18-28 (39.1%).
• The Pirates have played in 135 games with a set over/under, and have combined with their opponents to go over the total 53 times (53-76-6).
• The Pirates have covered 54.8% of their games this season, going 74-61-0 ATS.

Brewers Player Leaders

• William Contreras has 26 doubles, 17 home runs and 77 walks while batting .263. He has an on-base percentage of .359 and a slugging percentage of .411.
• Among all qualifying hitters in baseball, he ranks 64th in batting average, 25th in on-base percentage, and 95th in slugging.
• Contreras hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .293 with two doubles, two home runs, three walks and four RBIs.
• Brice Turang has hit 17 homers this season while driving in 71 runs. He's batting .291 this season and slugging .447 with an on-base percentage of .358.
• Among all qualifying hitters, he ranks 14th in batting average, 26th in on-base percentage and 66th in slugging percentage.
• Turang brings a two-game streak with at least one hit into this matchup. In his last five games he is batting .438 with a double, a triple, a home run, three walks and three RBIs.
• Christian Yelich has 134 hits this season and has a slash line of .268/.350/.464.
• Jackson Chourio leads Milwaukee in total hits (130) this season while batting .275 with 54 extra-base hits.

Pirates Player Leaders

• Bryan Reynolds has racked up a slugging percentage of .412 and has 129 hits, both team-best figures for the Pirates. He's batting .247 and with an on-base percentage of .316.
• Including all qualifying hitters, he ranks 99th in batting average, while his on-base percentage ranks 103rd and he is 92nd in slugging.
• Oneil Cruz is batting .203 with 17 doubles, two triples, 19 home runs and 60 walks. He's slugging .388 with an on-base percentage of .305.
• Including all qualifying hitters, he ranks 151st in batting average, 123rd in on-base percentage and 121st in slugging percentage.
• Andrew McCutchen has racked up a team-best .339 on-base percentage.
• Tommy Pham is hitting .261 with 17 doubles, a triple, eight home runs and 39 walks.

Brewers vs Pirates Head to Head

• 9/6/2025: 4-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/5/2025: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/13/2025: 12-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/12/2025: 14-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/11/2025: 7-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/25/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/24/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/23/2025: 5-4 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/25/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/24/2025: 2-1 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)

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