Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 1

Odds updated as of 1:12 p.m.

The MLB schedule on Monday includes the Houston Astros taking on the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this matchup.

Astros vs Angels Game Info

• Houston Astros (75-62) vs. Los Angeles Angels (64-72)
• Date: Monday, September 1, 2025
• Time: 2:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSW

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-162) | LAA: (+136)
• Spread: HOU: -1.5 (+128) | LAA: +1.5 (-154)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Luis Garcia (Astros) - 0-0, 0.00 ERA vs Yusei Kikuchi (Angels) - 6-9, 3.68 ERA

The probable starters are Luis Garcia for the Astros and Yusei Kikuchi (6-9) for the Angels. Garcia did not appear in a game when his team was the moneyline favorite last season. The Angels have a 16-12-0 record against the spread in Kikuchi's starts. The Angels are 6-11 in Kikuchi's 17 starts this season that they were the moneyline underdog.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.2%)

Astros vs Angels Moneyline

• The Astros vs Angels moneyline has Houston as a -162 favorite, while Los Angeles is a +136 underdog on the road.

Astros vs Angels Spread

• The Angels are +1.5 on the run line against the Astros. The Angels are -154 to cover, and the Astros are +128.

Astros vs Angels Over/Under

• The over/under for the Astros versus Angels contest on Sept. 1 has been set at 8.5, with -105 odds on the over and -115 odds on the under.

Bet on Houston Astros vs. Los Angeles Angels on FanDuel today!

Astros vs Angels Betting Trends

• The Astros have been favorites in 89 games this season and have come away with the win 47 times (52.8%) in those contests.
• This year Houston has won 14 of 27 games when listed as at least -162 on the moneyline.
• The Astros and their opponents have gone over the total this season in 60 of their 136 opportunities.
• The Astros have an against the spread mark of 67-69-0 in 136 games with a line this season.
• The Angels have compiled a 46-55 record in games they were the underdog on the moneyline (winning 45.5% of those games).
• When it has played as a moneyline underdog with odds of +136 or longer, Los Angeles has a record of 22-23 (48.9%).
• The Angels have played in 134 games with a set over/under, and have combined with their opponents to go over the total 71 times (71-58-5).
• The Angels are 73-61-0 ATS this season.

Astros Player Leaders

• Jose Altuve has an OPS of .785, fueled by an OBP of .335 and a team-best slugging percentage of .451 this season. He has a .273 batting average.
• Among qualified hitters in baseball, he is 39th in batting average, 66th in on-base percentage, and 62nd in slugging.
• Jeremy Pena has 128 hits and an OBP of .364, both of which lead the Astros this season. He's batting .305 and slugging .471.
• Among qualifying hitters, he ranks fourth in batting average, 21st in on-base percentage and 40th in slugging percentage.
• Christian Walker is batting .236 with a .410 slugging percentage and 74 RBI this year.
• Yainer Diaz has 18 home runs, 55 RBI and a batting average of .253 this season.

Angels Player Leaders

• Taylor Ward has 30 doubles, two triples, 30 home runs and 67 walks while hitting .228. He's slugging .476 with an on-base percentage of .318.
• Including all the qualified hitters in MLB, he is 143rd in batting average, 99th in on-base percentage and 37th in slugging percentage.
• Zach Neto paces his team with 123 hits and has a club-leading .486 slugging percentage. He has a batting average of .265 with an on-base percentage of .321.
• He is currently 61st in batting average, 94th in on-base percentage and 30th in slugging percentage among all qualified hitters.
• Jo Adell is batting .233 with 16 doubles, a triple, 30 home runs and 29 walks.
• Mike Trout paces his team with a .361 OBP.

Astros vs Angels Head to Head

• 8/31/2025: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/30/2025: 4-1 LAA (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/29/2025: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/22/2025: 8-7 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/21/2025: 9-1 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/20/2025: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 4/13/2025: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/12/2025: 4-1 LAA (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 4/11/2025: 14-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/22/2024: 9-8 LAA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)

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