Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 15

Odds updated as of 8:11 a.m.

The Friday slate in MLB includes a matchup between the New York Yankees and the St. Louis Cardinals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Yankees vs Cardinals Game Info

• New York Yankees (64-57) vs. St. Louis Cardinals (61-61)
• Date: Friday, August 15, 2025
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and YES

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-134) | STL: (+114)
• Spread: NYY: -1.5 (+120) | STL: +1.5 (-144)
• Total: 9 -- Over: (-102) | Under: (-120)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Luis Gil (Yankees) - 0-1, 7.27 ERA vs Andre Pallante (Cardinals) - 6-9, 4.95 ERA

This contest's pitching matchup is set, as the Yankees will send Luis Gil (0-1) to the mound, while Andre Pallante (6-9) will take the ball for the Cardinals. Gil has a record of 1-1-0 ATS in two starts with a spread this season. Gil's team is 1-1 this season when he starts and they're favored on the moneyline. The Cardinals are 12-11-0 against the spread when Pallante starts. The Cardinals have been the underdog on the moneyline in 14 of Pallante's starts this season, and they went 6-8 in those matchups.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.2%)

Yankees vs Cardinals Moneyline

• New York is the favorite, -134 on the moneyline, while St. Louis is a +114 underdog despite being at home.

Yankees vs Cardinals Spread

• The Yankees are favored by 1.5 runs on the road against the Cardinals. The Yankees are +120 to cover the spread, while the Cardinals are -144.

Yankees vs Cardinals Over/Under

• The Yankees-Cardinals game on Aug. 15 has been given an over/under of 9 runs. The over is set at -102 and the under at -120.

Bet on New York Yankees vs. St. Louis Cardinals on FanDuel today!

Yankees vs Cardinals Betting Trends

• The Yankees have been favorites in 100 games this season and have come away with the win 56 times (56%) in those contests.
• This season New York has come away with a win 45 times in 77 chances when named as a favorite of at least -134 on the moneyline.
• The Yankees and their opponents have hit the over in 54 of their 119 games with a total set by oddsmakers this season.
• In 119 games with a line this season, the Yankees have a mark of 51-68-0 against the spread.
• The Cardinals have won 50% of the games this season they were the moneyline underdog (31-31).
• St. Louis has a record of 14-19 in games it has played as a moneyline underdog with odds of +114 or longer (42.4%).
• The Cardinals have had an over/under set by bookmakers 117 times, and have combined with opponents to go over the total in 59 of those games (59-53-5).
• The Cardinals have put together a 60-57-0 record against the spread this season (covering 51.3% of the time).

Yankees Player Leaders

• Aaron Judge leads New York in OBP (.444), slugging percentage (.687) and total hits (134) this season. He has a .333 batting average.
• Among all qualified hitters in the majors, he ranks first in batting average, first in on-base percentage, and first in slugging.
• Cody Bellinger has 20 doubles, five triples, 22 home runs and 37 walks. He's batting .270 and slugging .491 with an on-base percentage of .325.
• He is 49th in batting average, 84th in on-base percentage and 27th in slugging among qualifying hitters.
• Anthony Volpe has 94 hits this season and has a slash line of .219/.288/.422.
• Volpe has picked up a hit in three straight games. In his last five games he is batting .176 with a double, a home run, three walks and three RBIs.
• Trent Grisham is batting .244 with a .346 OBP and 46 RBI for New York this season.
• Grisham has hit safely in three straight games. During his last five outings he is batting .300 with a home run, a walk and two RBIs.

Cardinals Player Leaders

• Brendan Donovan has put up a .348 on-base percentage and a .402 slugging percentage, both team-best numbers for the Cardinals. He's batting .279.
• He is 31st in batting average, 45th in on-base percentage and 105th in slugging percentage among all qualifying hitters in the majors.
• Alec Burleson has racked up 107 hits to pace his team. He has a batting average of .282 while slugging .450 with an on-base percentage of .334.
• He is currently 28th in batting average, 67th in on-base percentage and 63rd in slugging percentage among all qualifying hitters.
• Willson Contreras has 29 doubles, 16 home runs and 39 walks while hitting .255.
• Masyn Winn is batting .264 with 25 doubles, eight home runs and 30 walks.

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