Yankees vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 3

Odds updated as of 7:11 p.m.

The New York Yankees versus the Houston Astros is on the MLB schedule for Wednesday.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Astros Game Info

• New York Yankees (77-61) vs. Houston Astros (76-63)
• Date: Wednesday, September 3, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: MLB Network, SCHN, and Amazon Prime Video

Yankees vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-130) | HOU: (+110)
• Spread: NYY: -1.5 (+120) | HOU: +1.5 (-144)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Yankees vs Astros Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 8-6, 4.30 ERA vs Jason Alexander (Astros) - 4-1, 4.61 ERA

The Yankees will give the nod to Will Warren (8-6) against the Astros and Jason Alexander (4-1). Warren's team is 12-16-0 against the spread in his starts this season. Warren's team is 15-8 this season when he starts and they are the moneyline favorite. The Astros have gone 5-3-0 against the spread when Alexander starts. The Astros have played while the underdog on the moneyline for three of Alexander's starts this season, and they won every game.

Yankees vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (55.1%)

Yankees vs Astros Moneyline

• Houston is a +110 underdog on the moneyline, while New York is a -130 favorite on the road.

Yankees vs Astros Spread

• The Yankees are 1.5-run road favorites on the runline against the Astros. The Yankees are +120 to cover, and the Astros are -144.

Yankees vs Astros Over/Under

• A total of 8.5 runs has been set for the Yankees-Astros contest on Sept. 3, with the over available at -115 and the under at -105.

Bet on New York Yankees vs. Houston Astros on FanDuel today!

Yankees vs Astros Betting Trends

• The Yankees have been favorites in 115 games this season and have come away with the win 68 times (59.1%) in those contests.
• This season New York has come away with a win 60 times in 99 chances when named as a favorite of at least -130 on the moneyline.
• The Yankees and their opponents have hit the over in 66 of their 136 games with a total set by oddsmakers this season.
• In 136 games with a line this season, the Yankees have a mark of 63-73-0 against the spread.
• The Astros have a 26-19 record in games they were the underdog on the moneyline (winning 57.8% of those games).
• Houston is 15-10 (winning 60% of its games) when it has played as a moneyline underdog of +110 or longer.
• The Astros have combined with opponents to hit the over on the total 62 times this season for a 62-72-4 record against the over/under.
• The Astros have a 68-70-0 record ATS this season.

Yankees Player Leaders

• Aaron Judge has 151 hits and an OBP of .442 to go with a slugging percentage of .671. All three of those stats rank first among New York hitters this season. He has a .325 batting average, as well.
• Among the qualified hitters in baseball, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Judge has recorded a base hit in three straight games. During his last five outings he is batting .368 with a double, two home runs, six walks and two RBIs.
• Cody Bellinger is hitting .279 with 23 doubles, five triples, 26 home runs and 42 walks. He's slugging .501 with an on-base percentage of .332.
• He is 27th in batting average, 73rd in on-base percentage and 20th in slugging among qualified hitters.
• Bellinger takes a three-game streak with at least one hit into this contest. In his last five games he is hitting .273 with two doubles, a home run, two walks and four RBIs.
• Trent Grisham has 103 hits this season and has a slash line of .248/.357/.484.
• Jazz Chisholm has been key for New York with 92 hits, an OBP of .342 plus a slugging percentage of .505.

Astros Player Leaders

• Jose Altuve has racked up a slugging percentage of .456, a team-high for the Astros. He's batting .272 with an on-base percentage of .334.
• Including all qualified hitters, he is 39th in batting average, while his on-base percentage ranks 68th and he is 54th in slugging.
• Jeremy Pena has collected 130 hits with a .365 OBP to pace his team in both. He has a batting average of .304 while slugging .473.
• Including all qualifying players, his batting average places him fifth, his on-base percentage is 20th, and he is 39th in slugging.
• Yainer Diaz is hitting .253 with 18 doubles, a triple, 18 home runs and 19 walks.
• Christian Walker is batting .235 with 21 doubles, a triple, 21 home runs and 38 walks.

Yankees vs Astros Head to Head

• 9/2/2025: 7-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/10/2025: 7-1 HOU (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/9/2025: 5-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/8/2025: 5-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/9/2024: 4-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/8/2024: 9-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/7/2024: 10-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/31/2024: 4-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 3/30/2024: 5-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 3/29/2024: 7-1 NYY (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)

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