Twins vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 3

Odds updated as of 7:11 p.m.

The Minnesota Twins versus the Chicago White Sox is on the MLB schedule for Wednesday.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Twins vs White Sox Game Info

• Minnesota Twins (62-76) vs. Chicago White Sox (51-88)
• Date: Wednesday, September 3, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CHSN

Twins vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-174) | CHW: (+146)
• Spread: MIN: -1.5 (+115) | CHW: +1.5 (-138)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Twins vs White Sox Probable Starting Pitchers

Probable Pitchers: Zebby Matthews (Twins) - 4-4, 5.06 ERA vs Yoendrys Gomez (White Sox) - 3-2, 5.20 ERA

The Twins will give the ball to Zebby Matthews (4-4, 5.06 ERA), who is eyeing win No. 5 on the season, and the White Sox will turn to Yoendrys Gomez (3-2, 5.20 ERA). When Matthews starts, his team is 5-7-0 against the spread this season. When Matthews starts a game and his team is the favorite on the moneyline, they have a record of 4-3. The White Sox have gone 3-1-0 against the spread when Gomez starts. The White Sox have a 3-1 record in Gomez's four starts this season when they were the underdog on the moneyline.

Twins vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (68.4%)

Twins vs White Sox Moneyline

• Minnesota is the favorite, -174 on the moneyline, while Chicago is a +146 underdog on the road.

Twins vs White Sox Spread

• The White Sox are +1.5 on the spread (-138 to cover), and Minnesota is +115 to cover the runline.

Twins vs White Sox Over/Under

• A total of 8.5 runs has been set for the Twins-White Sox contest on Sept. 3, with the over available at -114 and the under at -106.

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Twins vs White Sox Betting Trends

• The Twins have been victorious in 39, or 49.4%, of the 79 contests they have been chosen as favorites in this season.
• This year Minnesota has won 10 of 16 games when listed as at least -174 on the moneyline.
• The Twins and their opponents have hit the over in 63 of their 133 games with a total set by oddsmakers this season.
• In 133 games with a line this season, the Twins have a mark of 65-68-0 against the spread.
• The White Sox have won 47 of the 131 games they were the moneyline underdog this season (35.9%).
• When it has played as a moneyline underdog with odds of +146 or longer, Chicago has a 19-46 record (winning only 29.2% of its games).
• The White Sox have combined with opponents to hit the over on the total 62 times this season for a 62-64-8 record against the over/under.
• The White Sox have covered 56% of their games this season, going 75-59-0 ATS.

Twins Player Leaders

• Byron Buxton leads Minnesota in total hits (110) this season while batting .272 with 51 extra-base hits. He has an on-base percentage of .333 and a slugging percentage of .553.
• Among all qualifying hitters in the majors, his batting average ranks 39th, his on-base percentage ranks 71st, and he is fifth in slugging.
• Buxton hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .282 with two doubles, a triple, four home runs, four walks and 11 RBIs.
• Trevor Larnach has an OPS of .741, fueled by an OBP of .327 and a team-best slugging percentage of .414 this season. He's batting .254.
• He is 88th in batting average, 84th in on-base percentage and 90th in slugging in MLB.
• Larnach has picked up at least one hit in four games in a row. In his last five games he is hitting .529 with a double, a walk and four RBIs.
• Brooks Lee has collected 101 base hits, an OBP of .293 and a slugging percentage of .383 this season.
• Lee brings a three-game hitting streak into this matchup. During his last five outings he is batting .158 with a walk and an RBI.
• Ryan Jeffers leads Minnesota with an OBP of .349 this season while batting .258 with 47 walks and 46 runs scored.

White Sox Player Leaders

• Andrew Benintendi has 15 doubles, two triples, 17 home runs and 34 walks while hitting .245. He's slugging .428 with an on-base percentage of .307.
• Lenyn Sosa's 118 hits and .436 slugging percentage are both team-highs. He has a batting average of .265 with an on-base percentage of .296.
• He is currently 58th in batting average, 136th in on-base percentage and 76th in slugging percentage among all qualifying batters.
• Chase Meidroth is batting .253 with 14 doubles, four home runs and 38 walks.
• Mike Tauchman is hitting .271 with 15 doubles, a triple, eight home runs and 40 walks.

Twins vs White Sox Head to Head

• 9/2/2025: 12-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/1/2025: 6-5 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/24/2025: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/23/2025: 7-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/22/2025: 9-7 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/24/2025: 3-0 CHW (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/23/2025: 6-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 4/22/2025: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 4/2/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 4/1/2025: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

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