Sabres vs Flames NHL Prediction, Odds, Picks, Best Bets for Nov. 19

In NHL action on Wednesday, the Buffalo Sabres take on the Calgary Flames.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NHL moneyline insights you need to know.

Sabres vs Flames Game Info

• Buffalo Sabres (7-8-4) vs. Calgary Flames (5-13-3)
• Date: Wednesday, November 19, 2025
• Time: 7:30 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Sabres vs Flames Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Sabres vs Flames Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (53.9%)

Sabres vs Flames Puck Line

• The Sabres are favored by 1.5 goals. The Sabres are +152 to cover the spread, with the Flames being -188.

Sabres vs Flames Over/Under

• An over/under of 6.5 has been set for Sabres-Flames on Nov. 19, with the over being +108 and the under -130.

Sabres vs Flames Moneyline

• The Sabres vs Flames moneyline has Buffalo as a -156 favorite, while Calgary is a +130 underdog on the road.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!