Rockets vs. Nuggets Prediction, Odds, Picks, Best Bets for Nov. 21

Rockets vs. Nuggets Game Info

• Date: Friday, November 21, 2025
• Time: 9:30 p.m. ET
• Venue: Toyota Center -- Houston, Texas
• Coverage: Amazon Prime Video

The Denver Nuggets (11-3) are slight underdogs (by 2 points) to build on a four-game road win streak when they visit the Houston Rockets (10-3) on Friday, November 21, 2025 at 9:30 p.m. ET. The matchup's over/under is 234.5.

Rockets vs. Nuggets Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Rockets vs. Nuggets Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Rockets win (62.7%)

Rockets vs. Nuggets Betting Trends

• The Rockets are 9-4-0 against the spread this season.
• The Nuggets are 9-5-0 against the spread this season.
• Rockets games have finished with a final combined score above the over/under 10 times out of 14 chances this season.
• The Nuggets have eclipsed the over/under 57.1% of the time this season (eight of 14 games with a set point total).
• In home games, Houston has a worse record against the spread (3-3-0) compared to its ATS record in away games (6-1-0).
• When playing at home, the Rockets eclipse the total 66.7% of the time (four of six games). They hit the over more often in road games, exceeding the total in 85.7% of games (six of seven).
• Denver's winning percentage against the spread at home is .714 (5-2-0). On the road, it is .571 (4-3-0).
• In terms of the over/under, Nuggets games have finished over 57.1% of the time this season, both at home (four of seven) and on the road (four of seven).

Rockets Leaders

• Alperen Sengun is averaging 23.4 points, 10.4 boards and 7.4 assists. At the other end, he averages 1.2 steals and 1 block.
• Kevin Durant is averaging 25.5 points, 4.5 boards and 3.4 assists. Defensively, he averages 0.9 steals and 0.6 blocked shots.
• Amen Thompson's numbers on the season are 16.8 points, 6.3 boards and 5.2 assists per contest, shooting 46.7% from the field.
• Jabari Smith Jr. is averaging 14.4 points, 6.6 boards and 1.7 assists.
• Reed Sheppard is averaging 12.5 points, 2.6 rebounds and 3 assists. At the other end, he averages 1.5 steals and 0.4 blocked shots.

Nuggets Leaders

• Per game, Nikola Jokic gives the Nuggets 29.1 points, 13.2 rebounds and 11.1 assists. He also averages 1.7 steals and 0.8 blocks.
• Jamal Murray's numbers on the season are 22.5 points, 5.2 boards and 6.2 assists per game. He is draining 46.1% of his shots from the floor and 35.2% from 3-point range, with an average of 2.5 treys.
• The Nuggets are getting 20.3 points, 6.3 boards and 1.4 assists per game from Aaron Gordon.
• Peyton Watson's numbers on the season are 8.2 points, 4.2 rebounds and 1.4 assists per contest. He is sinking 49.4% of his shots from the floor.
• Tim Hardaway Jr.'s numbers on the season are 11.1 points, 1.9 rebounds and 1.4 assists per game. He is draining 45.2% of his shots from the field and 45.3% from beyond the arc, with an average of 2.4 triples.

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