Rams vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 10

The Los Angeles Rams will take on the San Francisco 49ers in NFL action on Sunday.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.

Rams vs 49ers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Rams win (63.3%)

Rams vs 49ers Point Spread

The Rams are 3.5-point favorites against the 49ers. The Rams are -115 to cover the spread, while the 49ers are -105 to cover as a 3.5-point underdog.

Rams vs 49ers Over/Under

An over/under of 49.5 has been set for Rams-49ers on Nov. 9, with the over being -112 and the under -108.

Rams vs 49ers Moneyline

The moneyline numbers for Rams vs. 49ers reveal Los Angeles as the favorite (-205) and San Francisco as the underdog (+172) despite being the home team.

Rams vs 49ers Betting Trends

• Los Angeles' record against the spread is 6-2-0.
• The Rams' ATS record as 3.5-point favorites or more is 4-1.
• There have been three Rams games (out of eight) that went over the total this year.
• The 49ers have five wins in nine contests against the spread this year.
• San Francisco has won once ATS (1-1) as a 3.5-point underdog or greater this season.
• The 49ers have played nine games this season, and five of them have gone over the total.

Check out even more in-depth Rams vs. 49ers analysis on FanDuel Research.

Rams vs 49ers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAR: (-205) | SF: (+172)
• Spread: LAR: -3.5 (-115) | SF: +3.5 (-105)
• Total: 49.5 -- Over: (-112) | Under: (-108)

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