NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 7

The Houston Texans and the Seattle Seahawks take the field in one of many compelling matchups on the NFL schedule in Week 7.

Here are the betting odds to break down ahead of Week 7 in the NFL.

Bengals vs. Steelers

Ja'Marr Chase and the Cincinnati Bengals (2-4) play the Pittsburgh Steelers (4-1) on Thursday at 8:15 p.m. ET at Paycor Stadium.

• Game Preview: Pittsburgh Steelers at Cincinnati Bengals
• Projected Favorite: Steelers (74.10% win probability)
• Spread: Pittsburgh (-5.5)
• Total: 42.5 -- Over: (-115) | Under: (-105)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on Cincinnati vs. Pittsburgh with FanDuel Sportsbook.

Jaguars vs. Rams

One of the top running backs in football will be featured when Kyren Williams and the Los Angeles Rams (4-2) take on the Jacksonville Jaguars (4-2) on Sunday, October 19, 2025.

• Game Preview: Los Angeles Rams vs. Jacksonville Jaguars
• Projected Favorite: Rams (62.46% win probability)
• Spread: Los Angeles (-3)
• Total: 44.5 -- Over: (-115) | Under: (-105)
• Time: 9:30 a.m. ET
• Channel: NFL Network

Bet on Jacksonville vs. Los Angeles with FanDuel Sportsbook.

Chiefs vs. Raiders

Patrick Mahomes and the Kansas City Chiefs (3-3) will host Tre Tucker and the Las Vegas Raiders (2-4) on Sunday at 1 p.m. ET, in a matchup featuring two of the brightest stars in football.

• Game Preview: Las Vegas Raiders at Kansas City Chiefs
• Projected Favorite: Chiefs (85.38% win probability)
• Spread: Kansas City (-11.5)
• Total: 45.5 -- Over: (-112) | Under: (-108)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Kansas City vs. Las Vegas with FanDuel Sportsbook.

Vikings vs. Eagles

On Sunday, Oct. 19 at 1 p.m. ET, the Philadelphia Eagles (4-2) will try to rebound from their recent 34-17 loss to the Giants when they match up with the Minnesota Vikings (3-2) at U.S. Bank Stadium. The Vikings won their last tilt 21-17 versus the Browns.

• Game Preview: Philadelphia Eagles at Minnesota Vikings
• Projected Favorite: Vikings (55.21% win probability)
• Spread: Philadelphia (-2.5)
• Total: 43.5 -- Over: (-104) | Under: (-118)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Minnesota vs. Philadelphia with FanDuel Sportsbook.

Browns vs. Dolphins

While the Cleveland Browns sport the worst-ranked scoring offense in the league (13.7 points per game), they are in a prime spot to put up some points on Oct. 19 at 1 p.m. ET when they host the Miami Dolphins (1-5), who have the NFL's 29th-ranked scoring defense (29.0 points allowed per game).

• Game Preview: Miami Dolphins at Cleveland Browns
• Projected Favorite: Browns (52.46% win probability)
• Spread: Cleveland (-3)
• Total: 40.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Cleveland vs. Miami with FanDuel Sportsbook.

Titans vs. Patriots

The Tennessee Titans (1-5) play on Sunday at 1 p.m. ET at Nissan Stadium versus the New England Patriots (4-2).

• Game Preview: New England Patriots at Tennessee Titans
• Projected Favorite: Patriots (65.40% win probability)
• Spread: New England (-7)
• Total: 41.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tennessee vs. New England with FanDuel Sportsbook.

Jets vs. Panthers

Garrett Wilson and the New York Jets (0-6) play the Carolina Panthers (3-3) on Sunday at 1 p.m. ET at MetLife Stadium.

• Game Preview: Carolina Panthers at New York Jets
• Projected Favorite: Panthers (55.47% win probability)
• Spread: Carolina (-1.5)
• Total: 42.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New York vs. Carolina with FanDuel Sportsbook.

Bears vs. Saints

On Sunday, Oct. 19 at 1 p.m. ET, the Chicago Bears (3-2) will look to build upon their recent 25-24 victory against the Commanders when they go head to head against the New Orleans Saints (1-5) at Soldier Field. The Saints lost their previous game 25-19 to the Patriots.

• Game Preview: New Orleans Saints at Chicago Bears
• Projected Favorite: Bears (78.28% win probability)
• Spread: Chicago (-5.5)
• Total: 47.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Chicago vs. New Orleans with FanDuel Sportsbook.

Broncos vs. Giants

The Denver Broncos (4-2), who defeated against the Jets in their last game, host the New York Giants (2-4) at Empower Field at Mile High on Oct. 19 at 4:05 p.m. ET. The Giants picked up the W against the Eagles in their last game.

• Game Preview: New York Giants at Denver Broncos
• Projected Favorite: Broncos (80.60% win probability)
• Spread: Denver (-7)
• Total: 40.5 -- Over: (-104) | Under: (-118)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Denver vs. New York with FanDuel Sportsbook.

Chargers vs. Colts

Justin Herbert and the Los Angeles Chargers (4-2) will host Jonathan Taylor and the Indianapolis Colts (5-1) on Sunday at 4:05 p.m. ET, in a matchup featuring a pair of outstanding running backs.

• Game Preview: Indianapolis Colts at Los Angeles Chargers
• Projected Favorite: Colts (60.17% win probability)
• Spread: Los Angeles (-1.5)
• Total: 48.5 -- Over: (-110) | Under: (-110)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Los Angeles vs. Indianapolis with FanDuel Sportsbook.

Cowboys vs. Commanders

The Washington Commanders (3-3) and the Dallas Cowboys (2-3-1), who both lost their last game, will go head to head at 4:25 p.m. ET on Sunday, Oct. 19. In their previous games, the Commanders lost 25-24 to the Bears, and the Cowboys were defeated by the Panthers 30-27.

• Game Preview: Washington Commanders at Dallas Cowboys
• Projected Favorite: Commanders (58.43% win probability)
• Spread: Washington (-1.5)
• Total: 54.5 -- Over: (-115) | Under: (-105)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Dallas vs. Washington with FanDuel Sportsbook.

Cardinals vs. Packers

On Sunday at 4:25 p.m. ET, two excellent pass-catchers will be on display when Tucker Kraft and the Green Bay Packers (3-1-1) visit Trey McBride and the Arizona Cardinals (2-4).

• Game Preview: Green Bay Packers at Arizona Cardinals
• Projected Favorite: Packers (75.97% win probability)
• Spread: Green Bay (-6.5)
• Total: 44.5 -- Over: (-104) | Under: (-118)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Arizona vs. Green Bay with FanDuel Sportsbook.

49ers vs. Falcons

Christian McCaffrey, who ranks eighth-best in the league in receiving yards, will try to lead the way for the San Francisco 49ers (4-2) on Oct. 19 at 8:20 p.m. ET, when they host the Atlanta Falcons (3-2) and their first-ranked pass defense (139.4 passing yards allowed per game).

• Game Preview: Atlanta Falcons at San Francisco 49ers
• Projected Favorite: 49ers (57.20% win probability)
• Spread: San Francisco (-2.5)
• Total: 47.5 -- Over: (-104) | Under: (-118)
• Time: 8:20 p.m. ET
• Channel: NBC

Bet on San Francisco vs. Atlanta with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!