Lakers vs. Clippers Prediction, Odds, Picks, Best Bets for Nov. 25

Lakers vs. Clippers Game Info

• Date: Tuesday, November 25, 2025
• Time: 11 p.m. ET
• Venue: Crypto.com Arena -- Los Angeles, California
• Coverage: NBC/Peacock

The Los Angeles Lakers (12-4) will look to continue a four-game win streak when they host the Los Angeles Clippers (5-12) on Tuesday, November 25, 2025 at Crypto.com Arena as 6-point favorites. The contest airs at 11 p.m. ET on NBC/Peacock. The matchup has an over/under set at 227.5 points.

Lakers vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Lakers vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Lakers win (59.8%)

Lakers vs. Clippers Betting Trends

• The Lakers have covered the spread 11 times in 16 games with a set spread.
• Against the spread, the Clippers are 5-12-0 this year.
• This season, Lakers games have hit the over 10 times out of 17 chances.
• Clippers games this year have gone over the point total 58.8% of the time (10 out of 17 games with a set point total).
• The Lakers have done a better job covering the spread when playing on the road (7-3-0) than they have in home games (4-2-0).
• When it comes to point totals, the Lakers hit the over more often in home games, as they've eclipsed the total six times in six opportunities this season (100%). In road games, they have hit the over four times in 10 opportunities (40%).
• This year, the Clippers are 1-7-0 at home against the spread (.125 winning percentage). Away, they are 4-5-0 ATS (.444).
• In 2025-26, a higher percentage of the Clippers' games have finished above the over/under at home (62.5%, five of eight) than away (55.6%, five of nine).

Lakers Leaders

• Luka Doncic averages 34.5 points, 8.8 rebounds and 8.9 assists, shooting 46.7% from the floor and 31.1% from downtown, with 3.4 made 3-pointers per contest (eighth in league).
• Austin Reaves averages 27.6 points, 5.5 rebounds and 7.3 assists.
• Deandre Ayton averages 15.5 points, 8.4 boards and 0.9 assists.
• Jake Laravia's numbers on the season are 10.3 points, 4.3 rebounds and 2.3 assists per contest, shooting 48% from the floor and 34.6% from beyond the arc, with an average of 1.1 made treys.
• Rui Hachimura's numbers on the season are 15 points, 3.9 rebounds and 1.1 assists per contest, shooting 56.2% from the floor and 48.3% from beyond the arc (fourth in league), with an average of 1.9 made treys.

Clippers Leaders

• James Harden averages 27.8 points, 5.8 rebounds and 8.4 assists. He is also sinking 45.3% of his shots from the field and 38.8% from 3-point range, with 3.9 triples per game (third in league).
• Per game, Ivica Zubac provides the Clippers 17 points, 11.6 rebounds and 2.4 assists. He also averages 0.5 steals and 0.9 blocks.
• John Collins' numbers on the season are 11.2 points, 4.8 rebounds and 0.5 assists per contest. He is draining 48.4% of his shots from the field.
• Kris Dunn averages 7.1 points, 2.6 boards and 2.6 assists. He is draining 48.4% of his shots from the floor.
• Kawhi Leonard's numbers on the season are 23.7 points, 5.3 boards and 3.3 assists per contest. He is sinking 50% of his shots from the floor and 42.5% from 3-point range, with an average of 2.4 triples.

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