Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 13

Odds updated as of 3:11 p.m.

The MLB schedule on Wednesday includes the San Francisco Giants facing the San Diego Padres.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs Padres Game Info

• San Francisco Giants (59-61) vs. San Diego Padres (68-52)
• Date: Wednesday, August 13, 2025
• Time: 3:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SDPA

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-118) | SD: (-100)
• Spread: SF: +1.5 (-215) | SD: -1.5 (+176)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Giants vs Padres Probable Starting Pitchers

Probable Pitchers: Kai-Wei Teng (Giants) - 1-1, 5.40 ERA vs Nick Pivetta (Padres) - 11-4, 2.94 ERA

This contest's pitching matchup is set, as the Giants will send Kai-Wei Teng (1-1) to the mound, while Nick Pivetta (11-4) will answer the bell for the Padres. Teng and his team failed to cover the spread in his only opportunity this season as a starter. Teng has yet to start a game this season when his team was the moneyline favorite. The Padres have a 13-10-0 record against the spread in Pivetta's starts. The Padres have a 5-3 record in Pivetta's eight starts this season when they were the moneyline underdog.

Giants vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (59.2%)

Giants vs Padres Moneyline

• San Diego is the underdog, -100 on the moneyline, while San Francisco is a -118 favorite at home.

Giants vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Giants. The Padres are +176 to cover, while the Giants are -215 to cover as a 1.5-run underdog on the runline.

Giants vs Padres Over/Under

• The over/under for Giants-Padres on Aug. 13 is 7.5. The over is -112, and the under is -108.

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Giants vs Padres Betting Trends

• The Giants have been favorites in 76 games this season and have come away with the win 38 times (50%) in those contests.
• San Francisco has a record of 36-34 when favored by -118 or more this year.
• The Giants and their opponents have hit the over in 53 of their 120 games with a total set by oddsmakers this season.
• In 120 games with a line this season, the Giants have a mark of 50-70-0 against the spread.
• The Padres have won 27 of the 53 games they were the moneyline underdog this season (50.9%).
• San Diego has a 24-23 record (winning 51.1% of its games) when it has played as a moneyline underdog of -100 or longer.
• The Padres have had an over/under set by oddsmakers 118 times, and have combined with opponents to go over the total in 50 of those games (50-65-3).
• The Padres have put together a 65-53-0 record against the spread this season.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.379) and total hits (115) this season. He's batting .256 batting average while slugging .469.
• Among qualified batters in the majors, his batting average ranks 84th, his on-base percentage ranks 10th, and he is 41st in slugging.
• Devers will look for his third straight game with a hit in this contest. During his last five outings he is hitting .278 with three home runs, three walks and three RBIs.
• Jung Hoo Lee has 27 doubles, nine triples, six home runs and 38 walks. He's batting .256 and slugging .403 with an on-base percentage of .321.
• Among all qualifying batters, he ranks 84th in batting average, 96th in on-base percentage and 101st in slugging percentage.
• Lee has picked up at least one hit in two straight games. In his last five games he is hitting .222 with .
• Willy Adames has collected 100 base hits, an OBP of .311 and a slugging percentage of .396 this season.
• Heliot Ramos has an OPS of .750, fueled by an OBP of .342 and a team-best slugging percentage of .407 this season.

Padres Player Leaders

• Manny Machado has a slugging percentage of .489 and has 137 hits, both team-high numbers for the Padres. He's batting .297 and with an on-base percentage of .359.
• Including all the qualified hitters in the big leagues, his batting average places him ninth, his on-base percentage ranks 28th, and he is 26th in slugging.
• Machado enters this game on a three-game hitting streak. In his last five games he is hitting .222 with four walks.
• Fernando Tatis Jr. is hitting .263 with 21 doubles, two triples, 17 home runs and 67 walks. He's slugging .433 with an on-base percentage of .366.
• Including all qualifying hitters, his batting average places him 67th, his on-base percentage ranks 20th, and he is 75th in slugging.
• Luis Arraez is hitting .290 with 23 doubles, four triples, six home runs and 25 walks.
• Xander Bogaerts has 26 doubles, 10 home runs and 46 walks while batting .268.

Giants vs Padres Head to Head

• 8/12/2025: 5-1 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2025: 4-1 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/5/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 6-5 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2025: 3-2 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/2/2025: 1-0 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/30/2025: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/14/2024: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)

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