Celtics vs. Lakers Prediction, Odds, Picks, Best Bets for Dec. 5

Celtics vs. Lakers Game Info

• Date: Friday, December 5, 2025
• Time: 7 p.m. ET
• Venue: TD Garden -- Boston, Massachusetts
• Coverage: Amazon Prime Video and SportsNet LA

Two of the league's top scorers hit the court when Jaylen Brown (fifth, 29 PPG) and the Boston Celtics (13-9) host Luka Doncic (first, 35.3 PPG) and the Los Angeles Lakers (16-5) on Friday, December 5, 2025 at 7 p.m. ET on Amazon Prime Video and SportsNet LA. The Celtics are 7-point favorites. The over/under in the matchup is set at 223.5.

Celtics vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Celtics vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Celtics win (71%)

Celtics vs. Lakers Betting Trends

• The Celtics have gone 12-9-1 against the spread this season.
• Against the spread, the Lakers are 14-7-0 this season.
• Celtics games have gone over the total 10 times out of 21 chances this season.
• Lakers games this season have eclipsed the over/under 15 times in 21 opportunities (71.4%).
• When playing at home, Boston has the same winning percentage against the spread as it does on the road (.545).
• The Celtics have exceeded the total in a higher percentage of home games (54.5%) than road tilts (36.4%).
• Against the spread, Los Angeles has had better results away (8-3-0) than at home (6-4-0).
• In 2025-26, a higher percentage of the Lakers' games have finished above the over/under at home (100%, 10 of 10) compared to away (45.5%, five of 11).

Celtics Leaders

• Brown is averaging 29 points, 4.8 assists and 6 boards.
• Derrick White's numbers on the season are 17 points, 4 rebounds and 5.3 assists per contest, shooting 38.3% from the field and 32.4% from beyond the arc, with an average of 2.9 made 3-pointers.
• Payton Pritchard's numbers on the season are 17.3 points, 4.4 boards and 4.9 assists per game, shooting 44.7% from the floor and 33.5% from downtown, with an average of 2.7 made treys.
• Neemias Queta averages 10.1 points, 8.2 rebounds and 1.6 assists, shooting 66.4% from the floor (fourth in league).
• Anfernee Simons is averaging 13.7 points, 2.1 rebounds and 2.6 assists.

Lakers Leaders

• Doncic's numbers on the season are 35.3 points, 8.9 boards and 8.9 assists per game. He is also draining 47.8% of his shots from the floor and 34.1% from beyond the arc, with an average of 3.7 triples (fourth in league).
• The Lakers are getting 28.9 points, 5.7 rebounds and 6.8 assists per game from Austin Reaves.
• Per game, Deandre Ayton gets the Lakers 15.8 points, 8.6 boards and 0.9 assists, plus 0.7 steals and 1.1 blocks.
• The Lakers receive 13.9 points per game from Rui Hachimura, plus 3.6 rebounds and 0.9 assists.
• Jake Laravia's numbers on the season are 9.2 points, 4 rebounds and 1.9 assists per contest. He is making 47.4% of his shots from the field and 34.9% from beyond the arc, with an average of 1 triples.

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