Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 8:12 p.m.

The MLB slate on Tuesday includes the St. Louis Cardinals facing the Colorado Rockies.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (52-49) vs. Colorado Rockies (24-76)
• Date: Tuesday, July 22, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSMW

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-194) | COL: (+162)
• Spread: STL: -1.5 (-128) | COL: +1.5 (+106)
• Total: 11 -- Over: (-115) | Under: (-105)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Erick Fedde (Cardinals) - 3-9, 4.83 ERA vs Bradley Blalock (Rockies) - 0-2, 9.97 ERA

The Cardinals will give the ball to Erick Fedde (3-9, 4.83 ERA), who is eyeing win No. 4 on the season, and the Rockies will turn to Bradley Blalock (0-2, 9.97 ERA). Fedde's team is 9-8-0 against the spread in his starts this season. Fedde's team has a record of 1-3 this season when he starts and they are the favorite on the moneyline. The Rockies have gone 1-3-0 against the spread when Blalock starts. The Rockies were the underdog on the moneyline for four Blalock starts this season -- they lost every time.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (58.2%)

Cardinals vs Rockies Moneyline

• The moneyline numbers for Cardinals vs. Rockies reveal St. Louis as the favorite (-194) and Colorado as the underdog (+162) despite being the home team.

Cardinals vs Rockies Spread

• The Rockies are hosting the Cardinals, and are +1.5 on the runline. The Rockies are -128 to cover the spread, and the Cardinals are +106.

Cardinals vs Rockies Over/Under

• The Cardinals-Rockies game on July 22 has been given an over/under of 11 runs. The over is set at -115 and the under at -105.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been chosen as favorites in 44 games this year and have walked away with the win 24 times (54.5%) in those games.
• St. Louis has played as a favorite of -194 or more just one time this year and came away with a win in that game.
• Contests with the Cardinals have gone over the total set by oddsmakers in 52 of 98 chances this season.
• The Cardinals have an against the spread mark of 53-45-0 in 98 games with a line this season.
• The Rockies have won 22 of the 94 games they were listed as the moneyline underdog this season (23.4%).
• Colorado has a record of 12-54 in games it has played as a moneyline underdog with odds of +162 or longer (18.2%).
• The Rockies have played in 98 games with a set over/under, and have combined with their opponents to go over the total 39 times (39-56-3).
• The Rockies have covered only 39.8% of their games this season, going 39-59-0 against the spread.

Cardinals Player Leaders

• Brendan Donovan has an OPS of .788, fueled by an OBP of .364 to go with a slugging percentage of .425. He has a .293 batting average, as well.
• Among the qualifying hitters in baseball, his batting average ranks 12th, his on-base percentage ranks 27th, and he is 80th in slugging.
• Nolan Arenado is batting .244 with 15 doubles, a triple, 10 home runs and 26 walks, while slugging .386 with an on-base percentage of .303.
• He ranks 113th in batting average, 127th in on-base percentage and 122nd in slugging in the majors.
• Alec Burleson has 88 hits and is batting .289 this season.
• Willson Contreras has 13 home runs, 57 RBI and a batting average of .256 this season.
• Contreras takes a two-game hitting streak into this matchup. In his last five games he is batting .316 with three doubles, a home run, a walk and four RBIs.

Rockies Player Leaders

• Hunter Goodman has racked up 93 hits with a .324 on-base percentage and a .518 slugging percentage, all club-highs for the Rockies. He's batting .278.
• Including all qualifying hitters in MLB, he ranks 38th in batting average, 86th in on-base percentage and 16th in slugging percentage.
• Jordan Beck's .324 OBP leads his team. He has a batting average of .271 while slugging .457.
• Including all qualified players, he ranks 53rd in batting average, 86th in on-base percentage and 53rd in slugging percentage.
• Mickey Moniak is hitting .271 with 11 doubles, six triples, 14 home runs and 16 walks.
• Ryan McMahon has 15 doubles, a triple, 15 home runs and 47 walks while hitting .218.

Cardinals vs Rockies Head to Head

• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/26/2024: 10-8 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/25/2024: 5-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/24/2024: 7-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/9/2024: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/8/2024: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 6/7/2024: 8-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/6/2024: 3-2 COL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 8/6/2023: 1-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/5/2023: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -250, Underdog Moneyline: +205)

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