Padres vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for July 23

Odds updated as of 7:16 a.m.

MLB action on Wednesday includes the San Diego Padres taking on the Miami Marlins.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Marlins Game Info

• San Diego Padres (55-46) vs. Miami Marlins (47-53)
• Date: Wednesday, July 23, 2025
• Time: 12:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: FDSFL and SDPA

Padres vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-146) | MIA: (+124)
• Spread: SD: -1.5 (+115) | MIA: +1.5 (-138)
• Total: 8 -- Over: (-110) | Under: (-110)

Padres vs Marlins Probable Starting Pitchers

Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.64 ERA vs Sandy Alcantara (Marlins) - 4-9, 7.14 ERA

This contest's pitching matchup is set, as the Padres will send Dylan Cease (3-9) to the mound, while Sandy Alcantara (4-9) will take the ball for the Marlins. Cease and his team are 9-11-0 ATS this season when he starts. Cease's team has a record of 8-5 this season when he starts and they are the favorite on the moneyline. The Marlins have an 8-11-0 ATS record in Alcantara's 19 starts with a set spread. The Marlins have been the underdog on the moneyline in 16 of Alcantara's starts this season, and they went 7-9 in those games.

Padres vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (60.1%)

Padres vs Marlins Moneyline

• Looking at the moneyline for Padres-Marlins, San Diego is the favorite at -146, and Miami is +124 playing at home.

Padres vs Marlins Spread

• The Padres are favored by 1.5 runs on the road against the Marlins. The Padres are +115 to cover the spread, while the Marlins are -138.

Padres vs Marlins Over/Under

• Padres versus Marlins on July 23 has an over/under of 8 runs, with the odds on the over -110 and the under set at -110.

Bet on San Diego Padres vs. Miami Marlins on FanDuel today!

Padres vs Marlins Betting Trends

• The Padres have been favorites in 49 games this season and have come away with the win 30 times (61.2%) in those contests.
• This year San Diego has won 18 of 27 games when listed as at least -146 on the moneyline.
• The Padres and their opponents have gone over in 41 of their 99 games with a total set by sportsbooks this season.
• The Padres have an against the spread record of 55-44-0 in 99 games with a line this season.
• The Marlins have won 46.4% of the games this season they were the moneyline underdog (39-45).
• Miami is 23-26 (winning 46.9% of its games) when playing as a moneyline underdog of +124 or longer.
• The Marlins have combined with opponents to go over the total 45 times this season for a 45-51-0 record against the over/under.
• The Marlins have a 56-40-0 record against the spread this season.

Padres Player Leaders

• Manny Machado leads San Diego with 109 hits, batting .282 this season with 41 extra-base hits. He has an on-base percentage of .344 and a slugging percentage of .482.
• Among all qualified hitters in the majors, he ranks 30th in batting average, 58th in on-base percentage, and 31st in slugging.
• Fernando Tatis Jr. leads San Diego with an OBP of .362 this season while batting .262 with 55 walks and 67 runs scored. He's slugging .439.
• Among qualified hitters, he ranks 74th in batting average, 30th in on-base percentage and 69th in slugging percentage.
• Luis Arraez leads San Diego in slugging percentage (.392) powered by 27 extra-base hits.
• Arraez enters this game with five games in a row with at least one hit. In his last five games he is batting .400 with a double, a walk and two RBIs.
• Xander Bogaerts is batting .268 with a .345 OBP and 35 RBI for San Diego this season.
• Bogaerts has hit safely in three straight games. In his last five games he is batting .300 with three doubles, a home run, two walks and four RBIs.

Marlins Player Leaders

• Kyle Stowers has totaled 95 hits with a .372 on-base percentage, leading the Marlins in both categories. He's batting .295 and slugging .565.
• Including all the qualifying players in the majors, he is ninth in batting average, 19th in on-base percentage and sixth in slugging percentage.
• Otto Lopez is hitting .252 with 11 doubles, 11 home runs and 33 walks. He's slugging .392 with an on-base percentage of .326.
• Including all qualifying players, he ranks 99th in batting average, 79th in on-base percentage and 114th in slugging percentage.
• Xavier Edwards has accumulated a slugging percentage of .356, a team-best for the Marlins.
• Agustin Ramirez has 22 doubles, a triple, 14 home runs and 19 walks while batting .244.

Padres vs Marlins Head to Head

• 7/22/2025: 4-3 MIA (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/21/2025: 2-1 SD (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/28/2025: 10-8 MIA (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/27/2025: 8-6 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 7-6 MIA (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/10/2024: 9-8 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/9/2024: 6-2 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 5/29/2024: 9-1 MIA (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/28/2024: 4-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)

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