Astros vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 13

Odds updated as of 6:14 p.m.

The Houston Astros are among the MLB teams playing on Wednesday, versus the Boston Red Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Astros vs Red Sox Game Info

• Houston Astros (67-53) vs. Boston Red Sox (66-55)
• Date: Wednesday, August 13, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NESN

Astros vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-108) | BOS: (-108)
• Spread: HOU: +1.5 (-172) | BOS: -1.5 (+142)
• Total: 8.5 -- Over: (-132) | Under: (+108)

Astros vs Red Sox Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 9-5, 2.51 ERA vs Walker Buehler (Red Sox) - 7-6, 5.40 ERA

The Astros will give the nod to Hunter Brown (9-5, 2.51 ERA), who is eyeing win No. 10 on the season, and the Red Sox will counter with Walker Buehler (7-6, 5.40 ERA). Brown's team is 13-10-0 against the spread in his starts this season. When Brown starts a game and his team is the favorite on the moneyline, they have a record of 11-7. The Red Sox have a 12-8-0 record against the spread in Buehler's starts. The Red Sox are 4-5 in Buehler's nine starts this season that they were the underdog on the moneyline.

Astros vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (64.1%)

Astros vs Red Sox Moneyline

• The moneyline numbers for Astros vs. Red Sox reveal Houston as the favorite (-108) and Boston as the underdog (-108) on the road.

Astros vs Red Sox Spread

Astros vs Red Sox Over/Under

• The over/under for Astros-Red Sox on Aug. 13 is 8.5. The over is -132, and the under is +108.

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Astros vs Red Sox Betting Trends

• The Astros have won in 41, or 53.2%, of the 77 contests they have been named as odds-on favorites in this year.
• This season Houston has been victorious 42 times in 80 chances when named as a favorite of at least -108 on the moneyline.
• The Astros and their opponents have gone over in 53 of their 119 games with a total set by sportsbooks this season.
• In 119 games with a line this season, the Astros have a mark of 60-59-0 against the spread.
• The Red Sox have won 20 of the 43 games they were the moneyline underdog this season (46.5%).
• When playing as a moneyline underdog with odds of -108 or longer, Boston has a record of 20-23 (46.5%).
• The Red Sox have combined with opponents to hit the over on the total 59 times this season for a 59-56-5 record against the over/under.
• The Red Sox have put together a 68-52-0 record against the spread this season.

Astros Player Leaders

• Jose Altuve leads Houston in slugging percentage (.472) thanks to 40 extra-base hits. He has a .285 batting average and an on-base percentage of .349.
• Among all qualifying hitters, he ranks 22nd in batting average, his on-base percentage ranks 43rd, and he is 37th in slugging.
• Jeremy Pena leads the Astros in OBP (.374) and total hits (114) this season. He's batting .318 while slugging .486.
• Among qualified hitters, he ranks second in batting average, 13th in on-base percentage and 30th in slugging percentage.
• Pena brings a two-game streak with at least one hit into this matchup. During his last five outings he is hitting .227 with a home run, a walk and an RBI.
• Yainer Diaz has 102 hits this season and has a slash line of .251/.279/.414.
• Christian Walker has 16 home runs, 65 RBI and a batting average of .235 this season.

Red Sox Player Leaders

• Jarren Duran has put up an on-base percentage of .335 and a slugging percentage of .456. Both lead the Red Sox. He's batting .265.
• Including all the qualifying players in the big leagues, his batting average ranks 60th, his on-base percentage is 65th, and he is 58th in slugging.
• Ceddanne Rafaela has 24 doubles, three triples, 14 home runs and 20 walks while hitting .259. He's slugging .438 with an on-base percentage of .301.
• He is currently 77th in batting average, 131st in on-base percentage and 72nd in slugging percentage among all qualifying hitters.
• Trevor Story has 19 doubles, 18 home runs and 25 walks while batting .256.
• Wilyer Abreu leads his team with 85 hits.

Astros vs Red Sox Head to Head

• 8/12/2025: 14-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/11/2025: 7-6 HOU (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/3/2025: 6-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/2/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 2-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 4-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2024: 6-5 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/19/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/11/2024: 10-2 HOU (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/10/2024: 5-4 HOU (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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