Astros vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 15

Odds updated as of 5:17 a.m.

The Friday slate in MLB includes a matchup between the Houston Astros and the Baltimore Orioles.

We've got you covered, in terms of the vital information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Orioles Game Info

• Houston Astros (68-53) vs. Baltimore Orioles (55-66)
• Date: Friday, August 15, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-240) | BAL: (+198)
• Spread: HOU: -1.5 (-114) | BAL: +1.5 (-105)
• Total: 8 -- Over: (-105) | Under: (-115)

Astros vs Orioles Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Astros) - 11-5, 2.97 ERA vs Brandon Young (Orioles) - 0-6, 6.70 ERA

This contest's pitching matchup is set, as the Astros will send Framber Valdez (11-5) to the mound, while Brandon Young (0-6) will get the nod for the Orioles. Valdez and his team have a record of 10-12-0 against the spread when he starts. Valdez's team has won 61.1% of his starts when they are favored on the moneyline (11-7). The Orioles are 4-5-0 against the spread when Young starts. The Orioles have been the moneyline underdog in seven of Young's starts this season, and they went 1-6 in those games.

Astros vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (70.7%)

Astros vs Orioles Moneyline

• Looking at the moneyline for Astros-Orioles, Houston is the favorite at -240, and Baltimore is +198 playing on the road.

Astros vs Orioles Spread

• The Astros are favored by 1.5 runs at home against the Orioles. The Astros are -114 to cover the spread, while the Orioles are -105.

Astros vs Orioles Over/Under

• Astros versus Orioles on Aug. 15 has an over/under of 8 runs, with the odds on the over -105 and the under set at -115.

Bet on Houston Astros vs. Baltimore Orioles on FanDuel today!

Astros vs Orioles Betting Trends

• The Astros have won in 42, or 53.8%, of the 78 contests they have been named as odds-on favorites in this year.
• This year Houston has won three of five games when listed as at least -240 on the moneyline.
• The Astros and their opponents have gone over in 53 of their 120 games with a total set by sportsbooks this season.
• The Astros are 61-59-0 against the spread in their 120 games with a line set by sportsbooks this season.
• The Orioles have won 45.2% of the games this season they were the moneyline underdog (28-34).
• Baltimore has played as a moneyline underdog of +198 or longer in just two games this season, which it split 1-1.
• The Orioles have played in 118 games with a set over/under, and have combined with their opponents to go over the total 50 times (50-64-4).
• The Orioles have covered 44.9% of their games this season, going 53-65-0 ATS.

Astros Player Leaders

• Jose Altuve leads Houston in slugging percentage (.469) thanks to 40 extra-base hits. He has a .283 batting average and an on-base percentage of .348.
• Among all qualifying hitters in MLB, he ranks 25th in batting average, 45th in on-base percentage, and 39th in slugging.
• Jeremy Pena leads Houston with 115 hits and an OBP of .373 this season. He's batting .318 and slugging .492.
• Among all qualified, he is second in batting average, 14th in on-base percentage and 26th in slugging percentage.
• Pena heads into this game looking to extend his three-game hit streak. During his last five outings he is hitting .273 with two home runs, a walk and two RBIs.
• Yainer Diaz is batting .254 with a .423 slugging percentage and 53 RBI this year.
• Diaz has logged a hit or more in two straight games. In his last five games he is batting .250 with a home run and three RBIs.
• Christian Walker has been key for Houston with 102 hits, an OBP of .300 plus a slugging percentage of .394.

Orioles Player Leaders

• Gunnar Henderson has racked up an on-base percentage of .352, a slugging percentage of .468, and has 121 hits, all club-highs for the Orioles (while batting .283).
• He is 25th in batting average, 41st in on-base percentage and 42nd in slugging percentage among all qualifying batters in the big leagues.
• Henderson brings a seven-game hitting streak into this matchup. In his last 10 outings he is batting .265 with four doubles, a home run, three walks and five RBIs.
• Jackson Holliday has 16 doubles, two triples, 14 home runs and 29 walks while hitting .248. He's slugging .387 with an on-base percentage of .301.
• Including all qualified players, his batting average places him 105th, his on-base percentage is 131st, and he is 127th in slugging.
• Adley Rutschman is hitting .232 with 16 doubles, a triple, nine home runs and 37 walks.
• Jordan Westburg has nine doubles, a triple, 14 home runs and 14 walks while batting .265.

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