Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 26

Odds updated as of 11:11 a.m.

The MLB slate on Saturday includes the Houston Astros taking on the Athletics.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Astros vs Athletics Game Info

• Houston Astros (60-44) vs. Athletics (44-62)
• Date: Saturday, July 26, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-134) | OAK: (+114)
• Spread: HOU: -1.5 (+150) | OAK: +1.5 (-182)
• Total: 8.5 -- Over: (-128) | Under: (+104)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 9-4, 2.57 ERA vs Jacob Lopez (Athletics) - 3-6, 4.60 ERA

The Astros will call on Hunter Brown (9-4) versus the Athletics and Jacob Lopez (3-6). When Brown starts, his team is 12-8-0 against the spread this season. Brown's team has been victorious in 68.8% of the games he's started as the moneyline favorite with a record of 11-5. The Athletics have a 7-4-0 record against the spread in Lopez's starts. The Athletics have a 6-4 record in Lopez's 10 starts this season when they were the underdog on the moneyline.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (66.7%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -134 favorite, while the Athletics are a +114 underdog on the road.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are +150 to cover, while the Athletics are -182 to cover.

Astros vs Athletics Over/Under

• Astros versus Athletics, on July 26, has an over/under of 8.5, with the over being -128 and the under +104.

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Astros vs Athletics Betting Trends

• The Astros have been favorites in 70 games this season and have come away with the win 39 times (55.7%) in those contests.
• This year, the Astros have won 23 of 38 games when listed as at least -134 or better on the moneyline.
• The Astros and their opponents have hit the over in 43 of their 103 games with a total this season.
• The Astros are 53-50-0 against the spread in their 103 games that had a posted line this season.
• The Athletics have been the underdog on the moneyline 83 total times this season. They've gone 32-51 in those games.
• The Athletics have a record of 18-39 when they have played as a moneyline underdog with odds of +114 or longer (31.6%).
• The Athletics have combined with their opponents to go over the total 55 times this season for a 55-45-5 record against the over/under.
• The Athletics have put together a 53-52-0 record against the spread this season (covering 50.5% of the time).

Astros Player Leaders

• Jose Altuve leads Houston with a slugging percentage of .463, fueled by 35 extra-base hits. He has a .280 batting average and an on-base percentage of .343.
• Among all qualified batters, he is 32nd in batting average, his on-base percentage ranks 58th, and he is 49th in slugging.
• Yainer Diaz is batting .246 with 14 doubles, a triple, 13 home runs and 14 walks. He's slugging .403 with an on-base percentage of .276.
• His batting average is 111th among qualified players, his on-base percentage 155th, and his slugging percentage 104th.
• Christian Walker is batting .231 with a .378 slugging percentage and 53 RBI this year.
• Cam Smith is batting .263 with a .333 OBP and 43 RBI for Houston this season.

Athletics Player Leaders

• Brent Rooker has racked up 112 hits, a team-best for the Athletics. He's batting .273 and slugging .498 with an on-base percentage of .351.
• Including all the qualifying hitters in MLB, he is 49th in batting average, 45th in on-base percentage and 22nd in slugging percentage.
• Jacob Wilson has a .354 OBP while slugging .439. Both are team-highs. He has a batting average of .312.
• Including all qualified hitters, he ranks fifth in batting average, 36th in on-base percentage and 71st in slugging percentage.
• Tyler Soderstrom is batting .258 with 17 doubles, a triple, 19 home runs and 38 walks.
• Nick Kurtz is hitting .305 with 18 doubles, two triples, 23 home runs and 28 walks.

Astros vs Athletics Head to Head

• 7/25/2025: 15-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/24/2025: 5-2 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/19/2025: 6-4 OAK (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/18/2025: 11-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/17/2025: 13-3 HOU (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/16/2025: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)

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