Yankees vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 6:12 a.m.

Thursday's slate in the MLB includes a matchup between the New York Yankees and the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Yankees vs Astros Game Info

• New York Yankees (77-62) vs. Houston Astros (77-63)
• Date: Thursday, September 4, 2025
• Time: 7:40 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: MLB Network, SCHN, and YES

Yankees vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-142) | HOU: (+120)
• Spread: NYY: -1.5 (+114) | HOU: +1.5 (-137)
• Total: 9 -- Over: (-118) | Under: (-104)

Yankees vs Astros Probable Starting Pitchers

Probable Pitchers: Carlos Rodon (Yankees) - 15-7, 3.18 ERA vs Cristian Javier (Astros) - 1-1, 3.38 ERA

The probable starters are Carlos Rodon (15-7) for the Yankees and Cristian Javier (1-1) for the Astros. Rodon's team is 11-17-0 against the spread in his starts this season. Rodon's team has a record of 15-12 this season when he starts and they are the favorite on the moneyline. The Astros have gone 2-2-0 ATS in Javier's four starts that had a set spread. The Astros were the underdog on the moneyline for two Javier starts this season -- they won both.

Yankees vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (52.3%)

Yankees vs Astros Moneyline

• Looking at the moneyline for Yankees-Astros, New York is the favorite at -142, and Houston is +120 playing at home.

Yankees vs Astros Spread

• The Astros are hosting the Yankees, and are +1.5 on the runline. The Astros are +114 to cover the spread, and the Yankees are -137.

Yankees vs Astros Over/Under

• The Yankees-Astros game on Sept. 4 has been given an over/under of 9 runs. The over is set at -118 and the under at -104.

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Yankees vs Astros Betting Trends

• The Yankees have been favorites in 116 games this season and have come away with the win 68 times (58.6%) in those contests.
• New York has a record of 53-32 when favored by -142 or more this year.
• The Yankees' games have gone over the total in 67 of their 137 opportunities.
• The Yankees have an against the spread mark of 63-74-0 in 137 games with a line this season.
• The Astros have gone 27-19 in games they were the underdog on the moneyline (winning 58.7% of those games).
• When it has played as a moneyline underdog with odds of +120 or longer, Houston has a record of 9-3 (75%).
• The Astros have combined with opponents to go over the total 63 times this season for a 63-72-4 record against the over/under.
• The Astros have a 69-70-0 record ATS this season.

Yankees Player Leaders

• Aaron Judge leads New York in OBP (.440), slugging percentage (.666) and total hits (152) this season. He has a .323 batting average.
• Among qualifying batters, he is first in batting average, his on-base percentage ranks first, and he is first in slugging.
• Judge has hit safely in four straight games. In his last five games he is hitting .333 with a double, two home runs, four walks and two RBIs.
• Cody Bellinger is batting .278 with 23 doubles, five triples, 27 home runs and 43 walks, while slugging .505 with an on-base percentage of .332.
• He is 29th in batting average, 72nd in on-base percentage and 17th in slugging in MLB.
• Bellinger enters this matchup looking to extend his four-game hit streak. In his last five games he is batting .182 with a double, a home run, two walks and five RBIs.
• Trent Grisham has collected 103 base hits, an OBP of .355 and a slugging percentage of .480 this season.
• Jazz Chisholm has been key for New York with 93 hits, an OBP of .341 plus a slugging percentage of .501.
• Chisholm heads into this game on a two-game hitting streak. In his last five games he is batting .263 with a double, two home runs, four walks and four RBIs.

Astros Player Leaders

• Jose Altuve has a .452 slugging percentage, which leads the Astros. He's batting .270 with an on-base percentage of .332.
• Including all qualified hitters, he is 45th in batting average, while his on-base percentage ranks 72nd and he is 59th in slugging.
• Jeremy Pena leads his team with 132 hits and a .368 on-base percentage. He has a batting average of .306 while slugging .480.
• He ranks fifth in batting average, 15th in on-base percentage and 35th in slugging percentage in the big leagues.
• Yainer Diaz is hitting .253 with 19 doubles, a triple, 18 home runs and 19 walks.
• Christian Walker is batting .235 with 21 doubles, a triple, 21 home runs and 39 walks.

Yankees vs Astros Head to Head

• 9/3/2025: 8-7 HOU (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/2/2025: 7-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/10/2025: 7-1 HOU (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/9/2025: 5-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/8/2025: 5-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/9/2024: 4-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/8/2024: 9-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/7/2024: 10-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/31/2024: 4-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 3/30/2024: 5-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)

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