Twins vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 6:12 a.m.

On Thursday in MLB, the Minnesota Twins are up against the Chicago White Sox.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Twins vs White Sox Game Info

• Minnesota Twins (62-77) vs. Chicago White Sox (52-88)
• Date: Thursday, September 4, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CHSN

Twins vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-152) | CHW: (+128)
• Spread: MIN: -1.5 (+138) | CHW: +1.5 (-166)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Twins vs White Sox Probable Starting Pitchers

Probable Pitchers: Taj Bradley (Twins) - 6-7, 4.82 ERA vs Fraser Ellard (White Sox) - 0-2, 4.82 ERA

This contest's pitching matchup is set, as the Twins will send Taj Bradley (6-7) to the mound, while Fraser Ellard (0-2) will take the ball for the White Sox. Bradley's team is 10-13-0 against the spread this season in his starts. When Bradley starts a game and his team is the favorite on the moneyline, they have a record of 5-5. Ellard has started just one game with a set spread, which the White Sox covered. The White Sox were the moneyline underdog for one Ellard start this season -- they won.

Twins vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (62%)

Twins vs White Sox Moneyline

• Looking at the moneyline for Twins-White Sox, Minnesota is the favorite at -152, and Chicago is +128 playing on the road.

Twins vs White Sox Spread

• The White Sox are +1.5 on the spread (-166 to cover), and Minnesota is +138 to cover the runline.

Twins vs White Sox Over/Under

• The over/under for Twins-White Sox on Sept. 4 is 8.5. The over is -110, and the under is -110.

Bet on Minnesota Twins vs. Chicago White Sox on FanDuel today!

Twins vs White Sox Betting Trends

• The Twins have won in 39, or 48.8%, of the 80 contests they have been named as odds-on favorites in this year.
• This season Minnesota has come away with a win 17 times in 30 chances when named as a favorite of at least -152 on the moneyline.
• The Twins and their opponents have hit the over in 63 of their 134 games with a total set by oddsmakers this season.
• The Twins are 65-69-0 against the spread in their 134 games with a line set by sportsbooks this season.
• The White Sox have compiled a 48-84 record in games they were the underdog on the moneyline (winning 36.4% of those games).
• Chicago has a record of 32-62 when playing as a moneyline underdog with odds of +128 or longer (34%).
• The White Sox have combined with opponents to hit the over on the total 62 times this season for a 62-65-8 record against the over/under.
• The White Sox are 76-59-0 ATS this season.

Twins Player Leaders

• Byron Buxton leads Minnesota in slugging percentage (.559) and total hits (112) this season. He's batting .273 with an on-base percentage of .333.
• Among qualified batters in baseball, his batting average ranks 38th, his on-base percentage ranks 70th, and he is fifth in slugging.
• Buxton will look for his eighth straight game with a hit in this contest. In his last 10 outings he is batting .282 with three doubles, two triples, four home runs, three walks and 10 RBIs.
• Trevor Larnach leads Minnesota in slugging percentage (.413) thanks to 37 extra-base hits. He's batting .254 with an on-base percentage of .327.
• Among all qualifying players, he ranks 89th in batting average, 83rd in on-base percentage and 90th in slugging percentage.
• Larnach takes a five-game streak with at least one hit into this one. In his last five games he is batting .526 with a double, a walk and four RBIs.
• Brooks Lee has collected 101 base hits, an OBP of .290 and a slugging percentage of .379 this season.
• Ryan Jeffers has 101 hits this season and a team-best OBP of .352.

White Sox Player Leaders

• Andrew Benintendi is batting .244 with 15 doubles, two triples, 17 home runs and 35 walks. He's slugging .425 with an on-base percentage of .306.
• Lenyn Sosa's 119 hits and .434 slugging percentage both pace his team. He has a batting average of .265 with an on-base percentage of .295.
• Including all qualified hitters, his batting average puts him 60th, his on-base percentage ranks 137th, and he is 78th in slugging.
• Chase Meidroth is hitting .251 with 14 doubles, four home runs and 38 walks.
• Mike Tauchman is hitting .271 with 15 doubles, a triple, eight home runs and 40 walks.

Twins vs White Sox Head to Head

• 9/3/2025: 4-3 CHW (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 9/2/2025: 12-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/1/2025: 6-5 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/24/2025: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/23/2025: 7-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/22/2025: 9-7 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/24/2025: 3-0 CHW (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/23/2025: 6-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 4/22/2025: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 4/2/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)

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