Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for AL Wild Card Game 1 on Sept. 30

Odds updated as of 12:12 p.m.

In MLB action on Tuesday, the Detroit Tigers play the Cleveland Guardians in Game 1 of the AL Wild Card Series.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Guardians Game Info

• Detroit Tigers (87-75) vs. Cleveland Guardians (88-74)
• Date: Tuesday, September 30, 2025
• Time: 1:08 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: ESPN

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-168) | CLE: (+142)
• Spread: DET: -1.5 (+112) | CLE: +1.5 (-134)
• Total: 6 -- Over: (-114) | Under: (-106)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Tarik Skubal (Tigers) - 13-6, 2.21 ERA vs Gavin Williams (Guardians) - 12-5, 3.06 ERA

The probable starters are Tarik Skubal (13-6, 2.21 ERA) for the Tigers and Gavin Williams (12-5, 3.06 ERA) for the Guardians. Skubal and his team have a record of 13-16-0 against the spread when he starts. Skubal's team has won 66.7% of his starts when they are favored on the moneyline (18-9). The Guardians have a 15-16-0 ATS record in Williams' 31 starts that had a set spread. The Guardians have a 10-10 record in Williams' 20 starts this season when they were the moneyline underdog.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (59.4%)

Tigers vs Guardians Moneyline

• Detroit is a -168 favorite on the moneyline, while Cleveland is a +142 underdog at home.

Tigers vs Guardians Spread

• The Guardians are +1.5 on the run line against the Tigers. The Guardians are -134 to cover, and the Tigers are +112.

Tigers vs Guardians Over/Under

• The over/under for the Tigers versus Guardians contest on Sept. 30 has been set at 6, with -114 odds on the over and -106 odds on the under.

Bet on Detroit Tigers vs. Cleveland Guardians on FanDuel today!

Tigers vs Guardians Betting Trends

• The Tigers have been favorites in 105 games this season and have come away with the win 58 times (55.2%) in those contests.
• Detroit has a record of 25-16 when favored by -168 or more this year.
• The Tigers and their opponents have gone over the total this season in 78 of their 155 opportunities.
• The Tigers have posted a record of 71-84-0 against the spread this season.
• The Guardians have been the moneyline underdog 87 total times this season. They've gone 41-46 in those games.
• In games it has played as a moneyline underdog with odds of +142 or longer, Cleveland has gone 8-12 (40%).
• The Guardians have combined with opponents to go over the total 68 times this season for a 68-84-6 record against the over/under.
• The Guardians have an 85-73-0 record ATS this season.

Tigers Player Leaders

• Gleyber Torres has 136 hits this season and a team-best OBP of .358. He has a .256 batting average and a slugging percentage of .387.
• Among all qualified hitters in MLB, his batting average ranks 77th, his on-base percentage ranks 23rd, and he is 118th in slugging.
• Riley Greene has 155 hits to go with a slugging percentage of .493, both of which rank first among Detroit hitters this season. He's batting .258 with an on-base percentage of .313.
• He ranks 69th in batting average, 104th in on-base percentage and 21st in slugging in the majors.
• Spencer Torkelson is batting .240 with a .456 slugging percentage and 78 RBI this year.
• Zach McKinstry has 12 home runs, 49 RBI and a batting average of .259 this season.

Guardians Player Leaders

• Jose Ramirez has racked up a team-best OBP (.360), and paces the Guardians in hits (168). He's batting .283 and slugging.
• Including all qualifying players in the big leagues, he ranks 21st in batting average, 19th in on-base percentage and 16th in slugging percentage.
• Steven Kwan is slugging .374 to lead his team. He has a batting average of .272 with an on-base percentage of .330.
• He is 36th in batting average, 72nd in on-base percentage and 129th in slugging percentage in MLB.
• Kyle Manzardo has 19 doubles, two triples, 27 home runs and 48 walks while hitting .234.
• Angel Martinez is batting .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Tigers vs Guardians Head to Head

• 9/25/2025: 4-2 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/23/2025: 5-2 CLE (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/18/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/17/2025: 4-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/6/2025: 7-2 DET (Favorite: Tigers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 7/5/2025: 1-0 DET (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2025: 2-1 DET (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/25/2025: 5-0 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 5/24/2025: 7-5 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!