Tennessee vs Vanderbilt Prediction, Odds, Picks, Best Bets for Week 14 2025

On Saturday in college football, the Tennessee Volunteers are playing the Vanderbilt Commodores.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Tennessee vs Vanderbilt Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Tennessee: (-146) | Vanderbilt: (+124)
• Spread: Tennessee: -2.5 (-122) | Vanderbilt: +2.5 (100)
• Total: 65.5 -- Over: (-115) | Under: (-105)

Tennessee vs Vanderbilt Betting Trends

• Tennessee is 5-6-0 against the spread this season.
• Against the spread as 2.5-point or better favorites, Tennessee is 4-5.
• There have been seven Tennessee games (of 11) that hit the over this season.
• Vanderbilt's record against the spread in 2025 is 9-2-0.
• Vanderbilt has an ATS record of 3-1 as 2.5-point underdogs or greater.
• Vanderbilt has seen seven of its 11 games hit the over.

Tennessee vs Vanderbilt Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Volunteers win (51.1%)

Tennessee vs Vanderbilt Point Spread

Tennessee is a 2.5-point favorite against Vanderbilt. Tennessee is -122 to cover the spread, and Vanderbilt is +100.

Tennessee vs Vanderbilt Over/Under

Tennessee versus Vanderbilt on Nov. 29 has an over/under of 65.5 points, with the over -115 and the under -105.

Tennessee vs Vanderbilt Moneyline

Looking at the moneyline for Tennessee-Vanderbilt, Tennessee is the favorite at -146, and Vanderbilt is +124.

Tennessee vs. Vanderbilt Points Insights

Tennessee vs. Vanderbilt Game Info

• Game day: Saturday, November 29, 2025
• Game time: 3:30 p.m. ET
• TV channel: ESPN
• Location: Knoxville, Tennessee
• Stadium: Neyland Stadium

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Check out even more in-depth Tennessee vs. Vanderbilt analysis on FanDuel Research.