Tennessee vs Syracuse Prediction, Odds, Picks, Best Bets for Week 1 2025

College football's Saturday slate includes the Tennessee Volunteers taking on the Syracuse Orange.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

Tennessee vs Syracuse Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Tennessee: (-500) | Syracuse: (+375)
• Spread: Tennessee: -13.5 (-110) | Syracuse: +13.5 (-110)
• Total: 51.5 -- Over: (-115) | Under: (-105)

Tennessee vs Syracuse Betting Trends

• Tennessee had six wins in 12 games against the spread last season.
• Tennessee had two wins ATS (2-4) as 13.5-point or greater favorites last year.
• There were seven Tennessee games (out of 12) that hit the over last year.
• Syracuse posted a 6-7-0 record against the spread last year.
• There were eight Syracuse games (out of 13) that went over the total last season.

Tennessee vs Syracuse Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Volunteers win (85.3%)

Tennessee vs Syracuse Point Spread

Syracuse is the underdog by 13.5 points against Tennessee. Syracuse is -110 to cover the spread, and Tennessee is -110.

Tennessee vs Syracuse Over/Under

Tennessee versus Syracuse on Aug. 30 has an over/under of 51.5 points, with the over -115 and the under -105.

Tennessee vs Syracuse Moneyline

Tennessee is a -500 favorite on the moneyline, while Syracuse is a +375 underdog.

Tennessee vs. Syracuse Points Insights

• The average implied total for the Volunteers last season was 35.9 points, 2.9 more points than their implied total of 33 points in Saturday's game.
• The average implied point total last season for the Orange (33.4) is 14.4 more points than the team's implied total in this matchup (19).

Tennessee vs. Syracuse Game Info

• Game day: Saturday, August 30, 2025
• Game time: 12 p.m. ET
• TV channel: ABC
• Location: Atlanta, Georgia
• Stadium: Mercedes-Benz Stadium

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Check out even more in-depth Tennessee vs. Syracuse analysis on FanDuel Research.