Spurs vs. Cavaliers Prediction, Odds, Picks, Best Bets for Dec. 29

Spurs vs. Cavaliers Game Info

• Date: Monday, December 29, 2025
• Time: 8 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: NBC/Peacock

The Cleveland Cavaliers (17-16) visit the San Antonio Spurs (23-8) after losing three road games in a row. The Spurs are favored by just 3 points in the contest, which begins at 8 p.m. ET on Monday, December 29, 2025. The matchup has an over/under set at 243.5 points.

Spurs vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (55.6%)

Spurs vs. Cavaliers Betting Trends

• The Spurs are 16-12-3 against the spread this season.
• The Cavaliers have 11 wins against the spread in 33 games this year.
• Spurs games have gone over the total 15 times out of 33 chances this season.
• Cavaliers games this year have eclipsed the over/under 16 times in 33 opportunities (48.5%).
• At home, San Antonio owns a better record against the spread (8-4-2) compared to its ATS record in road games (8-8-1).
• The Spurs have eclipsed the total in six of 14 home games (42.9%). They've fared better in road games, eclipsing the total in nine of 17 matchups (52.9%).
• This year, Cleveland is 6-13-0 at home against the spread (.316 winning percentage). On the road, it is 5-9-0 ATS (.357).
• Cavaliers games have finished above the over/under less often at home (seven times out of 19) than on the road (nine of 14) this season.

Spurs Leaders

• Victor Wembanyama averages 23.9 points, 11.5 rebounds and 3.5 assists.
• Devin Vassell averages 15.3 points, 4 rebounds and 2.5 assists.
• De'Aaron Fox averages 21.9 points, 3.8 rebounds and 6.1 assists, shooting 48.2% from the floor and 39.4% from beyond the arc, with 2.4 made treys per contest.
• Stephon Castle is averaging 18.6 points, 7 assists and 5.1 boards.
• Keldon Johnson is averaging 13.3 points, 6.5 rebounds and 1.5 assists.

Cavaliers Leaders

• Donovan Mitchell averages 30.2 points, 4.5 rebounds and 5.4 assists. He is also draining 49.7% of his shots from the field and 39% from 3-point range, with 4 triples per contest (second in league).
• Evan Mobley's numbers on the season are 18.3 points, 9.1 rebounds and 4 assists per contest. He is sinking 49.5% of his shots from the field and 34.2% from 3-point range, with an average of 1.4 triples.
• Jaylon Tyson's numbers on the season are 13.4 points, 5.8 boards and 1.9 assists per game. He is draining 52.7% of his shots from the floor and 44.2% from 3-point range, with an average of 1.9 triples.
• De'Andre Hunter averages 14.8 points, 4.1 boards and 2.1 assists. He is draining 42.5% of his shots from the field and 31.2% from beyond the arc, with 1.8 triples per game.
• The Cavaliers receive 13.2 points per game from Jarrett Allen, plus 7.3 rebounds and 2 assists.

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