San Diego State vs Wyoming Prediction, Odds, Picks, Best Bets for Week 10 2025

The San Diego State Aztecs are among the college football teams in action on Saturday, up against the Wyoming Cowboys.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

San Diego State vs Wyoming Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: San Diego State: (-429) | Wyoming: (+340)
• Spread: San Diego State: -10.5 (-110) | Wyoming: +10.5 (-110)
• Total: 41.5 -- Over: (-115) | Under: (-105)

San Diego State vs Wyoming Betting Trends

• Against the spread, San Diego State is 6-1-0 this year.
• San Diego State has yet to lose ATS (1-0) as a 10.5-point favorite or greater this year.
• This year, three of San Diego State's seven games have hit the over.
• Against the spread, Wyoming is 5-3-0 this season.
• Wyoming has no wins ATS (0-2) as a 10.5-point underdog or more this season.
• Two Wyoming games (of eight) have hit the over this season.

San Diego State vs Wyoming Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Aztecs win (71.6%)

San Diego State vs Wyoming Point Spread

Wyoming is an underdog by 10.5 points against San Diego State. Wyoming is -110 to cover the spread, and San Diego State is -110.

San Diego State vs Wyoming Over/Under

San Diego State versus Wyoming, on Nov. 1, has an over/under of 41.5, with the over being -115 and the under -105.

San Diego State vs Wyoming Moneyline

Looking at the moneyline for San Diego State-Wyoming, San Diego State is the favorite at -429, and Wyoming is +340.

San Diego State vs. Wyoming Points Insights

San Diego State vs. Wyoming Game Info

• Game day: Saturday, November 1, 2025
• Game time: 7 p.m. ET
• TV channel: CBS Sports Network
• Location: San Diego, California
• Stadium: Snapdragon Stadium

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