Sabres vs Islanders NHL Prediction, Odds, Picks, Best Bets for Dec. 20

The Buffalo Sabres will face the New York Islanders in NHL action on Saturday.

Get the latest NHL odds ahead of this game on FanDuel Sportsbook.

Sabres vs Islanders Game Info

• Buffalo Sabres (15-14-4) vs. New York Islanders (19-13-3)
• Date: Saturday, December 20, 2025
• Time: 5 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Sabres vs Islanders Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Sabres vs Islanders Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (51.1%)

Sabres vs Islanders Puck Line

• The Sabres are favored by 1.5 goals (+130 to cover). New York, the underdog, is -160.

Sabres vs Islanders Over/Under

• Sabres versus Islanders on Dec. 20 has an over/under of 6.5 goals, with the over +102 and the under -124.

Sabres vs Islanders Moneyline

• Looking at the moneyline for Sabres-Islanders, Buffalo is the favorite at -184, and New York is +152 playing on the road.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!