Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 22

Odds updated as of 10:12 a.m.

In MLB action on Tuesday, the Tampa Bay Rays take on the Chicago White Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Rays vs White Sox Game Info

• Tampa Bay Rays (52-49) vs. Chicago White Sox (36-65)
• Date: Tuesday, July 22, 2025
• Time: 7:35 p.m. ET
• Venue: George M. Steinbrenner Field -- Tampa, Florida
• Coverage: FDSSUN and CHSN

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-230) | CHW: (+190)
• Spread: TB: -1.5 (-110) | CHW: +1.5 (-110)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Drew Rasmussen (Rays) - 7-5, 2.86 ERA vs Davis Martin (White Sox) - 2-7, 3.79 ERA

The Rays will give the nod to Drew Rasmussen (7-5) versus the White Sox and Davis Martin (2-7). Rasmussen's team is 9-8-0 against the spread this season in his starts. Rasmussen's team is 7-5 this season when he starts and they are the moneyline favorite. The White Sox have a 6-7-0 record against the spread in Martin's starts. The White Sox are 3-10 in Martin's 13 starts this season that they were the underdog on the moneyline.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (69.4%)

Rays vs White Sox Moneyline

• The Rays vs White Sox moneyline has Tampa Bay as a -230 favorite, while Chicago is a +190 underdog on the road.

Rays vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Rays. The White Sox are -110 to cover the spread, and the Rays are -110.

Rays vs White Sox Over/Under

• An over/under of 8.5 has been set for Rays-White Sox on July 22, with the over being -104 and the under -118.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have been favorites in 51 games this season and have come away with the win 30 times (58.8%) in those contests.
• Tampa Bay has played as a favorite of -230 or more just one time this year and came away with a win in that game.
• The Rays and their opponents have gone over the total this season in 39 of their 98 opportunities.
• The Rays have an against the spread mark of 45-53-0 in 98 games with a line this season.
• The White Sox have won 33 of the 95 games they were listed as the moneyline underdog this season (34.7%).
• Chicago has gone 3-25 in games it has played as a moneyline underdog with odds of +190 or longer (10.7%).
• The White Sox have played in 98 games with an over/under set, and have combined with opponents to go over the total 43 times (43-50-5).
• The White Sox have collected a 54-44-0 record ATS this season (covering 55.1% of the time).

Rays Player Leaders

• Yandy Diaz leads Tampa Bay in slugging percentage (.474) thanks to 36 extra-base hits. He has a .293 batting average and an on-base percentage of .352.
• He is 12th in batting average, 45th in on-base percentage, and 38th in slugging among all qualified hitters in baseball.
• Diaz hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is batting .333 with a double, two home runs, six walks and six RBIs.
• Junior Caminero has 97 hits, which ranks first among Tampa Bay batters this season. He's batting .259 with 45 extra-base hits. He's also slugging .513 with an on-base percentage of .299.
• He is 78th in batting average, 133rd in on-base percentage and 18th in slugging among qualified batters.
• Caminero takes a five-game streak with at least one hit into this one. In his last five games he is hitting .381 with a double, two home runs, a walk and five RBIs.
• Jonathan Aranda leads Tampa Bay in OBP (.394) this season, fueled by 103 hits.
• Brandon Lowe has been key for Tampa Bay with 87 hits, an OBP of .320 plus a slugging percentage of .480.

White Sox Player Leaders

• Miguel Vargas is hitting .223 with 25 doubles, two triples, 12 home runs and 38 walks. He's slugging .406 with an on-base percentage of .305.
• Including all the qualified hitters in MLB, his batting average is 144th, his on-base percentage ranks 125th, and he is 97th in slugging.
• Vargas brings a three-game hitting streak into this matchup. In his last five games he is batting .300 with four doubles, two home runs, four walks and five RBIs.
• Andrew Benintendi is batting .234 with 12 doubles, two triples, 11 home runs and 25 walks. He's slugging .429 with an on-base percentage of .303.
• Luis Robert is hitting .206 with nine doubles, 10 home runs and 34 walks.
• Chase Meidroth leads his team with a .333 on-base percentage.

Rays vs White Sox Head to Head

• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/27/2024: 8-7 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 4/26/2024: 9-4 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +194)
• 4/30/2023: 12-9 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/29/2023: 12-3 TB (Favorite: Rays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/28/2023: 3-2 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +138)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!