Rangers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 16

Odds updated as of 4:18 a.m.

Tuesday's slate in the MLB includes a matchup between the Texas Rangers and the Houston Astros.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Rangers vs Astros Game Info

• Texas Rangers (79-72) vs. Houston Astros (82-69)
• Date: Tuesday, September 16, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and RSN

Rangers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TEX: (-134) | HOU: (+114)
• Spread: TEX: -1.5 (+128) | HOU: +1.5 (-154)
• Total: 8 -- Over: (-110) | Under: (-110)

Rangers vs Astros Probable Starting Pitchers

Probable Pitchers: Merrill Kelly (Rangers) - 12-7, 3.21 ERA vs A.J. Blubaugh (Astros) - 3-1, 2.45 ERA

The probable pitchers are Merrill Kelly (12-7) for the Rangers and A.J. Blubaugh (3-1) for the Astros. Kelly's team is 14-13-0 against the spread this season in his starts. Kelly's team has been victorious in 58.8% of the games he's started as the moneyline favorite with a record of 10-7. Blubaugh has started just one game with a set spread, which the Astros failed to cover. The Astros have always been the moneyline underdog when Blubaugh starts this season.

Rangers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (50.3%)

Rangers vs Astros Moneyline

• Texas is a -134 favorite on the moneyline, while Houston is a +114 underdog at home.

Rangers vs Astros Spread

• The Astros are +1.5 on the run line against the Rangers. The Astros are -154 to cover, and the Rangers are +128.

Rangers vs Astros Over/Under

• An over/under of 8 has been set for Rangers-Astros on Sept. 16, with the over being -110 and the under -110.

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Rangers vs Astros Betting Trends

• The Rangers have come away with 45 wins in the 70 contests they have been listed as the favorites in this season.
• This season Texas has been victorious 27 times in 41 chances when named as a favorite of at least -134 on the moneyline.
• The Rangers and their opponents have gone over in 67 of their 150 games with a total set by sportsbooks this season.
• The Rangers are 82-68-0 against the spread in their 150 games that had a posted line this season.
• The Astros have won 56.6% of the games this season they were the moneyline underdog (30-23).
• Houston has a record of 17-10 in games it has played as a moneyline underdog with odds of +114 or longer (63%).
• The Astros have played in 150 games with an over/under set, and have combined with their opponents to go over the total 68 times (68-78-4).
• The Astros have gone 75-75-0 ATS this season.

Rangers Player Leaders

• Wyatt Langford leads Texas in OBP (.344) and total hits (117) this season. He's batting .245 batting average while slugging .433.
• Among all qualified hitters in the majors, he ranks 98th in batting average, 44th in on-base percentage, and 74th in slugging.
• Josh Smith leads Texas in slugging percentage (.371) thanks to 34 extra-base hits. He's batting .257 with an on-base percentage of .343.
• He is 76th in batting average, 48th in on-base percentage and 132nd in slugging in MLB.
• Adolis Garcia has 112 hits this season and has a slash line of .231/.274/.401.
• Josh Jung has been key for Texas with 110 hits, an OBP of .294 plus a slugging percentage of .394.

Astros Player Leaders

• Jose Altuve has put up a slugging percentage of .440, a team-high for the Astros. He's batting .262 with an on-base percentage of .325.
• Including all the qualified hitters in the majors, he ranks 62nd in batting average, 83rd in on-base percentage and 64th in slugging percentage.
• Jeremy Pena's 143 hits and .357 OBP both pace his team. He has a batting average of .299 while slugging .462.
• His batting average is seventh among all qualified players, his on-base percentage ranks 23rd, and he is 45th in slugging.
• Yainer Diaz is batting .257 with 22 doubles, a triple, 19 home runs and 20 walks.
• Christian Walker is batting .237 with 23 doubles, a triple, 23 home runs and 40 walks.

Rangers vs Astros Head to Head

• 9/15/2025: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/7/2025: 4-2 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/6/2025: 11-0 HOU (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/5/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/13/2025: 5-1 TEX (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/11/2025: 7-3 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/18/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/17/2025: 5-1 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/16/2025: 6-3 HOU (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)

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