Pistons vs. Cavaliers Prediction, Odds, Picks, Best Bets for Oct. 27

Pistons vs. Cavaliers Game Info

• Date: Monday, October 27, 2025
• Time: 7 p.m. ET
• Venue: Little Caesars Arena -- Detroit, Michigan
• Coverage: Peacock

The Cleveland Cavaliers (2-1) visit the Detroit Pistons (2-1) in a matchup of Central Division teams at Little Caesars Arena, starting at 7 p.m. ET on Monday, October 27, 2025. The Cavaliers are 2.5-point favorites in the game, the first matchup between the teams this season. The matchup has an over/under of 230.5 points.

Pistons vs. Cavaliers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Pistons vs. Cavaliers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (51.2%)

Pistons vs. Cavaliers Betting Trends

• The Cavaliers covered 47 times in 82 games with a spread last season.
• The Pistons' ATS record as underdogs of 2.5 points or greater was 20-14-4 last year.
• Cavaliers games hit the over 50 out of 82 times last season.
• Out of 82 Pistons games last season, 42 went over the total.
• In home games last season, Cleveland had a worse record against the spread (23-17-1) compared to its ATS record in away games (24-16-1).
• Detroit performed better against the spread on the road (23-16-2) than at home (19-20-2) last year.

Cavaliers Leaders

• Per game, Donovan Mitchell put up points, 4.5 rebounds and 5 assists last season. He also put up 1.3 steals and 0.2 blocks.
• Last season, Evan Mobley recorded an average of 18.5 points, 9.3 boards and 3.2 assists per game.
• Darius Garland recorded 20.6 points, 2.9 boards and 6.7 assists. He drained 47.2% of his shots from the field and 40.1% from 3-point range, with 2.8 treys per game.
• Jarrett Allen collected 13.5 points, 9.7 rebounds and 1.9 assists. He sank 70.6% of his shots from the floor (first in league).
• De'Andre Hunter collected 17 points, 4 boards and 1.4 assists per contest, plus 0.8 steals and 0.2 blocks.

Pistons Leaders

• Cade Cunningham's numbers last season were 26.1 points, 6.1 rebounds and 9.1 assists per contest, shooting 46.9% from the floor and 35.6% from downtown, with an average of 2.1 made treys.
• Jalen Duren put up 11.8 points, 2.7 assists and 10.3 rebounds.
• Tobias Harris' numbers last season were 13.7 points, 5.9 boards and 2.2 assists per game, shooting 47.7% from the field and 34.5% from beyond the arc, with an average of 1.2 made treys.
• Caris LeVert recorded 12.1 points, 3.4 assists and 3.2 rebounds.
• Ausar Thompson's stats last season were 10.1 points, 5.1 boards and 2.3 assists per game, shooting 53.5% from the floor.

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