Pirates vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 6:12 a.m.

Friday's slate in the MLB includes a matchup between the Pittsburgh Pirates and the Chicago White Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Pirates vs White Sox Game Info

• Pittsburgh Pirates (39-58) vs. Chicago White Sox (32-65)
• Date: Friday, July 18, 2025
• Time: 6:40 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and CHSN

Pirates vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-164) | CHW: (+138)
• Spread: PIT: -1.5 (+130) | CHW: +1.5 (-156)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Pirates vs White Sox Probable Starting Pitchers

Probable Pitchers: Bailey Falter (Pirates) - 6-4, 3.79 ERA vs Jonathan Cannon (White Sox) - 3-7, 4.44 ERA

The Pirates will look to Bailey Falter (6-4) versus the White Sox and Jonathan Cannon (3-7). Falter and his team have a record of 11-6-0 against the spread when he starts. Falter's team has been victorious in 75% of the games he's started as the moneyline favorite with a record of 3-1. When Cannon starts, the White Sox are 6-7-0 against the spread. The White Sox are 4-9 in Cannon's 13 starts this season that they were the underdog on the moneyline.

Pirates vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Pirates win (54.2%)

Pirates vs White Sox Moneyline

• Looking at the moneyline for White Sox-Pirates, Chicago is the underdog at +138, and Pittsburgh is -164 playing at home.

Pirates vs White Sox Spread

• The Pirates are favored by 1.5 runs at home against the White Sox. The Pirates are +130 to cover the spread, while the White Sox are -156.

Pirates vs White Sox Over/Under

• Pirates versus White Sox on July 18 has an over/under of 8.5 runs, with the odds on the over -115 and the under set at -105.

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Pirates vs White Sox Betting Trends

• The Pirates have been chosen as favorites in 22 games this year and have walked away with the win 11 times (50%) in those games.
• Pittsburgh has been listed as a favorite of -164 or more on two occasions this season and split those games.
• Contests with the Pirates have gone over the total set by sportsbooks in 34 of 90 chances this season.
• The Pirates are 46-44-0 against the spread in their 90 games with a line set by sportsbooks this season.
• The White Sox have been the moneyline underdog 91 total times this season. They've gone 29-62 in those games.
• Chicago has a 15-42 record (winning just 26.3% of its games) when it has played as a moneyline underdog of +138 or longer.
• The White Sox have played in 94 games with a set over/under, and have combined with opponents to go over the total 40 times (40-49-5).
• The White Sox have a 50-44-0 record ATS this season.

Pirates Player Leaders

• Oneil Cruz has 65 hits, which is best among Pittsburgh hitters this season, while batting .212 with 29 extra-base hits. He has an on-base percentage of .319 and a slugging percentage of .414.
• Among qualified hitters in MLB, his batting average ranks 146th, his on-base percentage ranks 99th, and he is 92nd in slugging.
• Cruz has recorded a base hit in five straight games. During his last five outings he is hitting .375 with a double, a home run, a walk and two RBIs.
• Andrew McCutchen leads Pittsburgh with an OBP of .335 this season while batting .255 with 36 walks and 30 runs scored. He's slugging .381.
• Among qualified hitters, his batting average places him 88th, his on-base percentage 72nd, and his slugging percentage 118th.
• Bryan Reynolds has hit 10 homers with a team-high .369 SLG this season.
• Reynolds has recorded a hit in two games in a row. During his last five outings he is batting .158 with a double and an RBI.
• Isiah Kiner-Falefa has one home run, 23 RBI and a batting average of .274 this season.

White Sox Player Leaders

• Miguel Vargas has racked up 74 hits with a .297 on-base percentage, leading the White Sox in both statistics. He's batting .218 and slugging .383.
• He ranks 142nd in batting average, 132nd in on-base percentage and 116th in slugging percentage among all qualifying hitters in MLB.
• Andrew Benintendi has 10 doubles, two triples, 11 home runs and 22 walks while batting .233. He's slugging .429 with an on-base percentage of .297.
• Chase Meidroth has seven doubles, two home runs and 32 walks while hitting .243.
• Lenyn Sosa is slugging .417 to lead his team.

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