Panthers vs Flames NHL Prediction, Odds, Picks, Best Bets for Nov. 28

The Friday slate in the NHL includes a matchup between the Florida Panthers and the Calgary Flames.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information about today's NHL betting odds.

Panthers vs Flames Game Info

• Florida Panthers (12-10-1) vs. Calgary Flames (8-14-3)
• Date: Friday, November 28, 2025
• Time: 4 p.m. ET
• Venue: Amerant Bank Arena -- Sunrise, Florida
• Coverage: ESPN+

Panthers vs Flames Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Flames Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Panthers win (66.1%)

Panthers vs Flames Puck Line

• The Flames are underdogs by 1.5 goals. The Flames are -158 to cover the spread, and the Panthers are +128.

Panthers vs Flames Over/Under

• A total of 5.5 goals has been set for the Panthers-Flames game on Nov. 28, with the over available at -120 and the under at -102.

Panthers vs Flames Moneyline

• Looking at the moneyline for Panthers-Flames, Florida is the favorite at -200, and Calgary is +164 playing on the road.

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