Padres vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 29

Odds updated as of 7:11 p.m.

The MLB slate on Friday includes the San Diego Padres facing the Minnesota Twins.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Twins Game Info

• San Diego Padres (75-59) vs. Minnesota Twins (60-73)
• Date: Friday, August 29, 2025
• Time: 8:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and SDPA

Padres vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SD: (-130) | MIN: (+110)
• Spread: SD: -1.5 (+134) | MIN: +1.5 (-162)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Padres vs Twins Probable Starting Pitchers

Probable Pitchers: Nestor Cortes (Padres) - 2-2, 4.66 ERA vs Zebby Matthews (Twins) - 3-4, 5.30 ERA

The Padres will give the nod to Nestor Cortes (2-2) versus the Twins and Zebby Matthews (3-4). Cortes' team is 3-3-0 against the spread this season in his starts. Cortes' team is 2-1 this season when he starts and they are the moneyline favorite. The Twins are 4-7-0 ATS in Matthews' 11 starts with a set spread. The Twins have a 2-2 record in Matthews' four starts this season when they were the moneyline underdog.

Padres vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.2%)

Padres vs Twins Moneyline

• Minnesota is the underdog, +110 on the moneyline, while San Diego is a -130 favorite despite being on the road.

Padres vs Twins Spread

• The Padres are at the Twins and are favored by 1.5 runs on the spread. The Padres are +134 to cover the runline, with the Twins being -162.

Padres vs Twins Over/Under

• The Padres-Twins game on Aug. 29 has been given an over/under of 8.5 runs. The over is set at -122 and the under at -100.

Bet on San Diego Padres vs. Minnesota Twins on FanDuel today!

Padres vs Twins Betting Trends

• The Padres have come away with 42 wins in the 67 contests they have been listed as the favorites in this season.
• This year San Diego has won 37 of 58 games when listed as at least -130 on the moneyline.
• The Padres and their opponents have gone over in 57 of their 132 games with a total set by sportsbooks this season.
• In 132 games with a line this season, the Padres have a mark of 74-58-0 against the spread.
• The Twins have been the moneyline underdog 49 total times this season. They've finished 18-31 in those games.
• In games it has played as a moneyline underdog with odds of +110 or longer, Minnesota has gone 9-16 (36%).
• The Twins have combined with opponents to hit the over on the total 58 times this season for a 58-63-7 record against the over/under.
• The Twins have put together a 63-65-0 record against the spread this season (covering 49.2% of the time).

Padres Player Leaders

• Fernando Tatis Jr. has 27 doubles, two triples, 18 home runs and 79 walks while batting .264. He has an on-base percentage of .370 and a slugging percentage of .434.
• Among qualifying batters in the majors, his batting average ranks 63rd, his on-base percentage ranks 14th, and he is 77th in slugging.
• Tatis hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .200 with two doubles, a home run, three walks and three RBIs.
• Manny Machado leads San Diego in slugging percentage (.471) and total hits (149) this season. He's batting .288 with an on-base percentage of .348.
• Among qualifiers, he is 17th in batting average, 43rd in on-base percentage and 44th in slugging percentage.
• Luis Arraez has 147 hits this season and has a slash line of .283/.316/.388.
• Xander Bogaerts is batting .262 with a .330 OBP and 49 RBI for San Diego this season.
• Bogaerts brings a three-game hitting streak into this game. In his last five games he is hitting .235 with a double, a walk and three RBIs.

Twins Player Leaders

• Byron Buxton has racked up a slugging percentage of .539 and has 104 hits, both team-best numbers for the Twins. He's batting .269 and with an on-base percentage of .331.
• Including all the qualifying hitters in the majors, he is 49th in batting average, 76th in on-base percentage and 10th in slugging percentage.
• Trevor Larnach is batting .242 with 19 doubles, a triple, 16 home runs and 45 walks. He's slugging .405 with an on-base percentage of .318.
• He is 114th in batting average, 99th in on-base percentage and 104th in slugging percentage in the majors.
• Brooks Lee is batting .249 with 13 doubles, a triple, 14 home runs and 25 walks.
• Ryan Jeffers' .347 on-base percentage paces his team.

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