Padres vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 5:18 a.m.
The San Diego Padres versus the Washington Nationals is on the MLB schedule for Friday.
Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.
Padres vs Nationals Game Info
- San Diego Padres (52-44) vs. Washington Nationals (38-58)
- Date: Friday, July 18, 2025
- Time: 6:45 p.m. ET
- Venue: Nationals Park -- Washington, District of Columbia
- Coverage: MASN and SDPA
Padres vs Nationals Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: SD: (-156) | WSH: (+132)
- Spread: SD: -1.5 (+106) | WSH: +1.5 (-128)
- Total: 8.5 -- Over: (-114) | Under: (-106)
Padres vs Nationals Probable Starting Pitchers
Probable Pitchers: Dylan Cease (Padres) - 3-9, 4.88 ERA vs Mike Soroka (Nationals) - 3-7, 5.35 ERA
The Padres will give the nod to Dylan Cease (3-9) versus the Nationals and Mike Soroka (3-7). When Cease starts, his team is 8-11-0 against the spread this season. Cease's team has won 58.3% of his starts when they are favored on the moneyline (7-5). When Soroka starts, the Nationals are 5-8-0 against the spread. The Nationals have a 3-9 record in Soroka's 12 starts this season when they were the underdog on the moneyline.
Padres vs Nationals Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (57.3%)
Padres vs Nationals Moneyline
- The Padres vs Nationals moneyline has San Diego as a -156 favorite, while Washington is a +132 underdog at home.
Padres vs Nationals Spread
- The Padres are at the Nationals and are favored by 1.5 runs on the spread. The Padres are +106 to cover the runline, with the Nationals being -128.
Padres vs Nationals Over/Under
- Padres versus Nationals on July 18 has an over/under of 8.5 runs, with the odds on the over -114 and the under set at -106.
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Padres vs Nationals Betting Trends
- The Padres have won in 28, or 59.6%, of the 47 contests they have been named as odds-on favorites in this year.
- San Diego has a record of 14-9 when favored by -156 or more this year.
- Contests with the Padres have gone over the total set by sportsbooks in 39 of 95 chances this season.
- The Padres are 51-44-0 against the spread in their 95 games that had a posted line this season.
- The Nationals have been the moneyline underdog 73 total times this season. They've gone 33-40 in those games.
- Washington is 16-23 (winning 41% of its games) when it has played as a moneyline underdog of +132 or longer.
- The Nationals have played in 91 games with an over/under set, and have combined with their opponents to go over the total 51 times (51-38-2).
- The Nationals are 47-44-0 against the spread this season.
Padres Player Leaders
- Fernando Tatis Jr. leads San Diego with an OBP of .366 this season while batting .269 with 51 walks and 65 runs scored. He has a slugging percentage of .451.
- He ranks 60th in batting average, 27th in on-base percentage, and 62nd in slugging among qualified hitters in baseball.
- Tatis will look for his seventh straight game with a hit in this contest. In his last 10 outings he is batting .343 with two doubles, a triple, a home run, 10 walks and four RBIs.
- Manny Machado leads San Diego with 107 hits and a team-best slugging percentage of .490. He's batting .292 with an on-base percentage of .350.
- Among qualifying hitters, his batting average places him 17th, his on-base percentage 49th, and his slugging percentage 27th.
- Luis Arraez is batting .279 with a .389 slugging percentage and 35 RBI this year.
- Gavin Sheets has 14 home runs, 50 RBI and a batting average of .265 this season.
Nationals Player Leaders
- James Wood has accumulated an on-base percentage of .381, a slugging percentage of .534, and has 99 hits, all club-highs for the Nationals (while batting .278).
- Including all the qualified hitters in the majors, his batting average is 45th, his on-base percentage is 12th, and he is 14th in slugging.
- C.J. Abrams is batting .287 with 20 doubles, four triples, 12 home runs and 24 walks. He's slugging .483 with an on-base percentage of .353.
- He is 22nd in batting average, 44th in on-base percentage and 32nd in slugging percentage in the majors.
- Luis Garcia has 20 doubles, seven home runs and 18 walks while batting .259.
- Nathaniel Lowe is batting .227 with 14 doubles, two triples, 14 home runs and 34 walks.
Padres vs Nationals Head to Head
- 6/25/2025: 1-0 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
- 6/24/2025: 4-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
- 6/23/2025: 10-6 WSH (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
- 7/25/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
- 7/24/2024: 12-3 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
- 7/23/2024: 4-0 SD (Favorite: Nationals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
- 6/26/2024: 8-5 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
- 6/25/2024: 9-7 SD (Favorite: Nationals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
- 6/24/2024: 7-6 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
- 6/25/2023: 8-3 WSH (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -215, Underdog Moneyline: +180)
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