Ole Miss vs Mississippi State Prediction, Odds, Picks, Best Bets for Week 14 2025

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The Friday schedule in college football includes a matchup between the Ole Miss Rebels and the Mississippi State Bulldogs.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Ole Miss vs Mississippi State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Ole Miss: (-280) | Mississippi State: (+230)
Spread: Ole Miss: -7.5 (100) | Mississippi State: +7.5 (-122)
Total: 62.5 -- Over: (-115) | Under: (-105)

Against the spread, Ole Miss is 6-5-0 this year.
As 7.5-point favorites or more, Ole Miss is 3-4 against the spread.
Ole Miss has played 11 games this season, and six of them have gone over the total.
Mississippi State is 8-3-0 against the spread this year.
Mississippi State has an ATS record of 3-2 as 7.5-point underdogs or greater.
There have been six Mississippi State games (out of 11) that hit the over this season.

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (74.4%)

Mississippi State is listed as an underdog by 7.5 points (-122 odds), and Ole Miss, the favorite, is +100 to cover.

An over/under of 62.5 has been set for Ole Miss-Mississippi State on Nov. 28, with the over being -115 and the under -105.

Ole Miss is the favorite, -280 on the moneyline, while Mississippi State is a +230 underdog.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Ole Miss	37.2	15	20.2	28	57.3	11
Mississippi State	31.5	43	28.4	92	56.1	11

Check out even more in-depth Ole Miss vs. Mississippi State analysis on FanDuel Research.

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