Nuggets vs. Spurs Prediction, Odds, Picks, Best Bets for Nov. 28

Nuggets vs. Spurs Game Info

• Date: Friday, November 28, 2025
• Time: 9:30 p.m. ET
• Venue: Ball Arena -- Denver, Colorado
• Coverage: ALT and KENS

The Denver Nuggets (13-4) hit the court against the San Antonio Spurs (12-5) as heavy, 10-point favorites on Friday, November 28, 2025 at 9:30 p.m. ET on ALT and KENS. The point total for the matchup is 236.5.

Nuggets vs. Spurs Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Nuggets vs. Spurs Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Nuggets win (72.9%)

Nuggets vs. Spurs Betting Trends

• The Nuggets have put together an 11-6-0 record against the spread this season.
• The Spurs have played 17 games, with seven wins against the spread.
• Nuggets games have gone over the total 10 times this season.
• Spurs games this year have hit the over 47.1% of the time (eight out of 17 games with a set point total).
• At home, Denver owns a worse record against the spread (5-3-0) compared to its ATS record in road games (6-3-0).
• The Nuggets have gone over the over/under in a higher percentage of games at home (62.5%) than away games (55.6%).
• San Antonio has been better against the spread at home (5-3-2) than away (2-4-1) this season.
• Looking at the over/under, Spurs games have finished over less often at home (four of 10, 40%) than away (four of seven, 57.1%).

Nuggets Leaders

• Nikola Jokic averages 29.6 points, 12.8 rebounds and 11.1 assists.
• Jamal Murray is averaging 23.2 points, 6.8 assists and 4.6 boards.
• Peyton Watson is averaging 9.8 points, 1.6 assists and 4.8 rebounds.
• Cameron Johnson is averaging 9.9 points, 2.1 assists and 3.3 rebounds.
• Tim Hardaway Jr.'s numbers on the season are 11.1 points, 1.9 boards and 1.4 assists per game, shooting 44.8% from the floor and 41.5% from downtown, with an average of 2.3 made 3-pointers.

Spurs Leaders

• Devin Vassell averages 14.4 points for the Spurs, plus 3.8 boards and 2.4 assists.
• Keldon Johnson averages 12.5 points, 6.5 rebounds and 1.8 assists. He is also making 57.5% of his shots from the field.
• The Spurs are getting 12.9 points, 3.2 rebounds and 2.1 assists per game from Harrison Barnes.
• The Spurs are getting 25 points, 3.9 rebounds and 6.3 assists per game from De'Aaron Fox.
• Per game, Julian Champagnie provides the Spurs 10.5 points, 5.2 boards and 1.4 assists, plus 0.9 steals and 0.4 blocks.

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