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Tampa Bay Buccaneers Vs. Buffalo Bills Odds, Betting Lines, Score & Stats (November 16, 2025) | FanDuel Research

FanDuel Research>
NFL>
Matchups>
Tampa Bay Buccaneers Vs. Buffalo Bills

CBS

Tampa Bay Buccaneers

6-3 | 1st in NFC South | 4th in NFC

SpreadMoneylineTotal

@

Buffalo Bills

6-3 | 2nd in AFC East | 6th in AFC

SpreadMoneylineTotal

CBS

Highmark Stadium

Featured Player Props

View all NFL Player Props

Type

Passing Yards

Receiving Yards

Rushing Yards

Passing Touchdowns

Josh Allen

QB • 238 Average YD

Baker Mayfield

QB • 244 Average YD

Line Movement

These graphs show how the spread, moneyline, and total have shifted at FanDuel Sportsbook over time.

Spread

TB

Open: +6.5

BUF

Open: -6.5

Moneyline

TB

Open: +215

BUF

Open: -260

Total

Over

Open: 49.5

Under

Open: 49.5

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Tampa Bay Buccaneers

QBBaker Mayfield

17.3 Points

14.0 Points

RBRachaad White

11.5 Points

9.5 Points

Buffalo Bills

22.3 Points

18.5 Points

WRKhalil Shakir

11.0 Points

8.5 Points

TB

BUF

5.3336

Offensive EPA

13.578

7.3337

Passing EPA

15.6147

4.0002

Rushing EPA

10.8624

1.3334

Defensive EPA

5.4312

2.6668

Def Pass EPA

0.6789

0.6667

Def Rush EPA

10.8624

NFL

4 Best NFL Bets and Predictions for Week 11

4 Best NFL Bets and Predictions for Week 11

Jim Sannes

• 10h

The Lions have a big road test in NFL Week 11 as they face the Eagles. Can Detroit pull off the upset?

NFL Week 11 Spread and Total Predictions for Every Game

Jim Sannes

• 12h

NFL Week 11 Spread and Total Predictions for Every Game

Week 11 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

FanDuel Staff

• 14h

Week 11 NFL Odds: Predictions, Spreads, Moneylines, and Totals for Each Game

Eagles vs Lions Prediction, Odds, Picks, Best Bets for NFL Week 11

Data Skrive

• 1d

Eagles vs Lions Prediction, Odds, Picks, Best Bets for NFL Week 11

NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 11

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Popular Bets

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Check back closer to game time!

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

4 Leg Parlay

+2000

Player

Any Time Touchdown Scorer

Player 40+ Yards

Player - Alt Rushing Yds

Player 250+ Yards

Player - Alt Passing Yds

Player 5+ Receptions

Player - Alt Receptions

1425 People Placed

Tampa Bay Buccaneers

NameStatus

OLBHaason Reddick

QAnkle

WRMike Evans

IRCollarbone

WRChris Godwin Jr.

OLower Leg

NTVita Vea

QBack

TEKo Kieft

IRLeg

CBAntoine Winfield Jr.

QFoot

Buffalo Bills

NameStatus

OLBShaq Thompson

QHamstring

DEJoey Bosa

QWrist

PCameron Johnston

QFoot

DBCam Lewis

QCalf

KTyler Bass

IRHip

SAFTaylor Rapp

IRKnee

Tampa Bay Buccaneers

DateOpponentResultSpread

vs

NEL 28 - 23-2.5

@

NOW 23 - 3-5.5

@

DETL 9 - 24+4.5

vs

SFW 19 - 30-3

@

SEAW 38 - 35+3

vs

PHIL 31 - 25+3.5

Buffalo Bills

DateOpponentResultSpread

@

MIAL 13 - 30-9.5

vs

KCW 21 - 28+2.5

@

CARW 40 - 9-7.5

@

ATLL 14 - 24-3.5

vs

NEL 23 - 20-8.5

vs

NOW 19 - 31-16.5