NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 17

The Los Angeles Rams and the Atlanta Falcons hit the field for one of many exciting matchups on the NFL schedule in Week 17.

To get an edge prior to Week 17 in the NFL, read our odds breakdown below.

Commanders vs. Cowboys

The Dallas Cowboys (6-8-1) and Javonte Williams, one of the league's top runners, should have a productive day running the ball on Thursday, as the Washington Commanders (4-11) have the 29th-ranked run defense in the NFL. The two teams will compete at 1 p.m. ET on Dec. 25.

• Game Preview: Dallas Cowboys at Washington Commanders
• Projected Favorite: Cowboys (58.90% win probability)
• Spread: Dallas (-8.5)
• Total: 50.5 -- Over: (-106) | Under: (-114)
• Time: 1 p.m. ET
• Channel: Netflix

Bet on Washington vs. Dallas with FanDuel Sportsbook.

Vikings vs. Lions

Jared Goff, who ranks third-best in the NFL in passing yards, will try to lead the charge for the Detroit Lions (8-7) on Dec. 25 at 4:30 p.m. ET, when they visit the Minnesota Vikings (7-8) and their third-best pass D (169.2 passing yards allowed per game).

• Game Preview: Detroit Lions at Minnesota Vikings
• Projected Favorite: Lions (67.21% win probability)
• Spread: Detroit (-7.5)
• Total: 43.5 -- Over: (-115) | Under: (-105)
• Time: 4:30 p.m. ET
• Channel: Netflix

Bet on Minnesota vs. Detroit with FanDuel Sportsbook.

Chiefs vs. Broncos

The Denver Broncos (12-3) and the Kansas City Chiefs (6-9), who were both defeated in their last contest, will go head to head at 8:15 p.m. ET on Thursday, Dec. 25. In their previous games, the Broncos lost 34-20 to the Jaguars, and the Chiefs were taken down by the Titans 26-9.

• Game Preview: Denver Broncos at Kansas City Chiefs
• Projected Favorite: Broncos (79.03% win probability)
• Spread: Denver (-13.5)
• Total: 37.5 -- Over: (-120) | Under: (-102)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on Kansas City vs. Denver with FanDuel Sportsbook.

Chargers vs. Texans

Nico Collins and the Houston Texans (10-5) play the Los Angeles Chargers (11-4) on Saturday at 4:30 p.m. ET at SoFi Stadium.

• Game Preview: Houston Texans at Los Angeles Chargers
• Projected Favorite: Chargers (58.42% win probability)
• Spread: Los Angeles (-1.5)
• Total: 39.5 -- Over: (-110) | Under: (-110)
• Time: 4:30 p.m. ET
• Channel: NFL Network

Bet on Los Angeles vs. Houston with FanDuel Sportsbook.

Packers vs. Ravens

Derrick Henry will lead the Baltimore Ravens (7-8) into their game against the Green Bay Packers (9-5-1) at Lambeau Field, on Saturday at 8 p.m. ET.

• Game Preview: Baltimore Ravens at Green Bay Packers
• Spread: Green Bay (-2.5)
• Total: 37.5 -- Over: (-118) | Under: (-104)
• Time: 8 p.m. ET
• Channel: Peacock

Bet on Green Bay vs. Baltimore with FanDuel Sportsbook.

Colts vs. Jaguars

The 1 p.m. ET contest on Dec. 28 between the Indianapolis Colts (8-7) and the Jacksonville Jaguars (11-4) should be a competitive matchup, as Jonathan Taylor has been one of the league's top runners this year, and the Jaguars have been a top-five run defense, ranking first in the NFL with 87.3 rushing yards allowed per contest.

• Game Preview: Jacksonville Jaguars at Indianapolis Colts
• Projected Favorite: Jaguars (62.89% win probability)
• Spread: Jacksonville (-4.5)
• Total: 48.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Indianapolis vs. Jacksonville with FanDuel Sportsbook.

Dolphins vs. Buccaneers

The Tampa Bay Buccaneers (7-8), who were defeated by the Panthers in their last tilt, visit the Miami Dolphins (6-9) at Hard Rock Stadium on Dec. 28 at 1 p.m. ET. The Dolphins lost to the Bengals in their last game.

• Game Preview: Tampa Bay Buccaneers at Miami Dolphins
• Projected Favorite: Buccaneers (54.36% win probability)
• Spread: Tampa Bay (-5.5)
• Total: 44.5 -- Over: (-108) | Under: (-112)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Miami vs. Tampa Bay with FanDuel Sportsbook.

Bengals vs. Cardinals

The Cincinnati Bengals (5-10) and their 29th-ranked pass defense might struggle to slow down the Arizona Cardinals (3-12) and Trey McBride, one of the league's top pass-catchers, when the Cardinals visit the Bengals at Paycor Stadium on Dec. 28 at 1 p.m. ET.

• Game Preview: Arizona Cardinals at Cincinnati Bengals
• Projected Favorite: Bengals (63.78% win probability)
• Spread: Cincinnati (-7)
• Total: 53.5 -- Over: (-106) | Under: (-114)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Cincinnati vs. Arizona with FanDuel Sportsbook.

Panthers vs. Seahawks

The Seattle Seahawks (12-3) are set to square off against the Carolina Panthers (8-7) at Bank of America Stadium on Sunday, Dec. 28 at 1 p.m. ET. Both squads won their previous contest, as the Seahawks defeated the Rams 38-37, and the Panthers won 23-20 versus the Buccaneers.

• Game Preview: Seattle Seahawks at Carolina Panthers
• Projected Favorite: Seahawks (69.20% win probability)
• Spread: Seattle (-7)
• Total: 42.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Carolina vs. Seattle with FanDuel Sportsbook.

Jets vs. Patriots

Star QB Drake Maye and the New England Patriots (12-3) face the New York Jets (3-12) on Sunday at 1 p.m. ET at MetLife Stadium.

• Game Preview: New England Patriots at New York Jets
• Projected Favorite: Patriots (72.91% win probability)
• Spread: New England (-13.5)
• Total: 42.5 -- Over: (-114) | Under: (-106)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New York vs. New England with FanDuel Sportsbook.

Titans vs. Saints

Chris Olave will lead the New Orleans Saints (5-10) into their battle against the Tennessee Titans (3-12) at Nissan Stadium on Sunday at 1 p.m. ET.

• Game Preview: New Orleans Saints at Tennessee Titans
• Projected Favorite: Saints (63.50% win probability)
• Spread: New Orleans (-1.5)
• Total: 39.5 -- Over: (-104) | Under: (-118)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tennessee vs. New Orleans with FanDuel Sportsbook.

Browns vs. Steelers

On Sunday, Dec. 28 at 1 p.m. ET, the Pittsburgh Steelers (9-6) will attempt to build upon their recent 29-24 victory over the Lions when they take on the Cleveland Browns (3-12) at Huntington Bank Field. The Browns lost their last tilt 23-20 to the Bills.

• Game Preview: Pittsburgh Steelers at Cleveland Browns
• Projected Favorite: Steelers (58.09% win probability)
• Spread: Pittsburgh (-4.5)
• Total: 35.5 -- Over: (-108) | Under: (-112)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Cleveland vs. Pittsburgh with FanDuel Sportsbook.

Raiders vs. Giants

The Las Vegas Raiders (2-13) have struggled to generate points this season, ranking dead last in the NFL at 14.5 points per game. But they might have success on Dec. 28 at 4:05 p.m. ET when they host the New York Giants (2-13), who rank just 28th in scoring defense (27.5 points allowed per game).

• Game Preview: New York Giants at Las Vegas Raiders
• Projected Favorite: Giants (59.55% win probability)
• Spread: New York (-2.5)
• Total: 41.5 -- Over: (-108) | Under: (-112)
• Time: 4:05 p.m. ET
• Channel: CBS

Bet on Las Vegas vs. New York with FanDuel Sportsbook.

Bills vs. Eagles

The Buffalo Bills (11-4), who rank third in the league by scoring 28.9 points per game, will be tested by the third-ranked scoring defense of the Philadelphia Eagles (10-5), who allow opponents to score 19.3 per game. The game begins at 4:25 p.m. ET on Sunday, Dec. 28 at Highmark Stadium.

• Game Preview: Philadelphia Eagles at Buffalo Bills
• Projected Favorite: Bills (59.94% win probability)
• Spread: Buffalo (-3)
• Total: 44.5 -- Over: (-110) | Under: (-110)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Buffalo vs. Philadelphia with FanDuel Sportsbook.

49ers vs. Bears

The San Francisco 49ers (11-4) and the Chicago Bears (11-4), who both took home a win in their last game, will go head to head at 8:20 p.m. ET on Sunday, Dec. 28. In their previous games, the 49ers won 48-27 against the Colts, and the Bears secured the win against the Packers 22-16.

• Game Preview: Chicago Bears at San Francisco 49ers
• Projected Favorite: 49ers (57.67% win probability)
• Spread: San Francisco (-3.5)
• Total: 51.5 -- Over: (-106) | Under: (-114)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on San Francisco vs. Chicago with FanDuel Sportsbook.

Falcons vs. Rams

The Los Angeles Rams (11-4), who lost to the Seahawks in their last tilt, visit the Atlanta Falcons (6-9) at Mercedes-Benz Stadium on Dec. 29 at 8:15 p.m. ET. The Falcons took down the Cardinals in their last game.

• Game Preview: Los Angeles Rams at Atlanta Falcons
• Projected Favorite: Rams (74.42% win probability)
• Spread: Los Angeles (-7.5)
• Total: 49.5 -- Over: (-105) | Under: (-115)
• Time: 8:15 p.m. ET
• Channel: ESPN

Bet on Atlanta vs. Los Angeles with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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