NFL Games This Week: Predictions, Odds, Picks, Best Bets for Week 11

The Week 11 NFL slate has plenty of exciting matchups in store. Among those games is the Seattle Seahawks taking on the Los Angeles Rams.

If you're looking for additional betting intel for Week 11 in the NFL, we've got you covered with betting odds for each of the big games.

Patriots vs. Jets

Star QB Drake Maye and the New England Patriots (8-2) play the New York Jets (2-7) on Thursday at 8:15 p.m. ET at Gillette Stadium.

• Game Preview: New York Jets at New England Patriots
• Projected Favorite: Patriots (85.38% win probability)
• Spread: New England (-12.5)
• Total: 43.5 -- Over: (-102) | Under: (-120)
• Time: 8:15 p.m. ET
• Channel: Amazon Prime Video

Bet on New England vs. New York with FanDuel Sportsbook.

Dolphins vs. Commanders

Against the Washington Commanders (3-7), who sport the 31st-ranked pass defense this season, Jaylen Waddle and the Miami Dolphins (3-7) shouldn't have any trouble moving the ball through the air when the two teams square off on Sunday, Nov. 16 at 9:30 a.m. ET. Waddle has been one of the NFL's top receivers this year, ranking 10th-best in the league in receiving yards.

• Game Preview: Washington Commanders vs. Miami Dolphins
• Projected Favorite: Dolphins (54.62% win probability)
• Spread: Miami (-2.5)
• Total: 47.5 -- Over: (-104) | Under: (-118)
• Time: 9:30 a.m. ET
• Channel: NFL Network

Bet on Miami vs. Washington with FanDuel Sportsbook.

Vikings vs. Bears

On Sunday, Nov. 16 at 1 p.m. ET, the Minnesota Vikings (4-5) will attempt to bounce back from their recent 27-19 loss to the Ravens when they go head to head against the Chicago Bears (6-3) at U.S. Bank Stadium. The Bears won their last tilt 24-20 versus the Giants.

• Game Preview: Chicago Bears at Minnesota Vikings
• Projected Favorite: Bears (54.74% win probability)
• Spread: Minnesota (-3)
• Total: 47.5 -- Over: (-120) | Under: (-102)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Minnesota vs. Chicago with FanDuel Sportsbook.

Steelers vs. Bengals

The Cincinnati Bengals (3-6) and Ja'Marr Chase, one of the NFL's top receivers, should have a big day through the air on Sunday, as the Pittsburgh Steelers (5-4) have the worst pass defense in the NFL. The two teams will square off at 1 p.m. ET on Nov. 16.

• Game Preview: Cincinnati Bengals at Pittsburgh Steelers
• Projected Favorite: Steelers (64.65% win probability)
• Spread: Pittsburgh (-5.5)
• Total: 49.5 -- Over: (-102) | Under: (-120)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Pittsburgh vs. Cincinnati with FanDuel Sportsbook.

Falcons vs. Panthers

On Sunday at 1 p.m. ET, two of the best offensive performers in football will be on display when wide receiver Drake London and the Atlanta Falcons (3-6) host running back Rico Dowdle and the Carolina Panthers (5-5).

• Game Preview: Carolina Panthers at Atlanta Falcons
• Projected Favorite: Falcons (58.50% win probability)
• Spread: Atlanta (-3.5)
• Total: 41.5 -- Over: (-118) | Under: (-104)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Atlanta vs. Carolina with FanDuel Sportsbook.

Jaguars vs. Chargers

One of the top quarterbacks in football will be featured when Justin Herbert and the Los Angeles Chargers (7-3) visit the Jacksonville Jaguars (5-4) on Sunday, November 16, 2025.

• Game Preview: Los Angeles Chargers at Jacksonville Jaguars
• Projected Favorite: Chargers (63.26% win probability)
• Spread: Los Angeles (-3)
• Total: 43.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Jacksonville vs. Los Angeles with FanDuel Sportsbook.

Giants vs. Packers

Star running back Josh Jacobs and the Green Bay Packers (5-3-1) meet the New York Giants (2-8) on Sunday at 1 p.m. ET at MetLife Stadium.

• Game Preview: Green Bay Packers at New York Giants
• Projected Favorite: Packers (76.59% win probability)
• Spread: Green Bay (-7)
• Total: 44.5 -- Over: (-102) | Under: (-120)
• Time: 1 p.m. ET
• Channel: FOX

Bet on New York vs. Green Bay with FanDuel Sportsbook.

Titans vs. Texans

At 1 p.m. ET on Sunday, the Houston Texans (4-5) play at the Tennessee Titans (1-8).

• Game Preview: Houston Texans at Tennessee Titans
• Projected Favorite: Texans (79.88% win probability)
• Spread: Houston (-6.5)
• Total: 37.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Tennessee vs. Houston with FanDuel Sportsbook.

Bills vs. Buccaneers

At Highmark Stadium on Sunday, Josh Allen and the Buffalo Bills (6-3) face Emeka Egbuka and the Tampa Bay Buccaneers (6-3) in a matchup between a pair of the brightest stars in football, starting at 1 p.m. ET.

• Game Preview: Tampa Bay Buccaneers at Buffalo Bills
• Projected Favorite: Bills (73.54% win probability)
• Spread: Buffalo (-5.5)
• Total: 47.5 -- Over: (-120) | Under: (-102)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Buffalo vs. Tampa Bay with FanDuel Sportsbook.

Rams vs. Seahawks

On Sunday at 4:05 p.m. ET, a pair of star pass-catchers will be on display when Puka Nacua and the Los Angeles Rams (7-2) host Jaxon Smith-Njigba and the Seattle Seahawks (7-2).

• Game Preview: Seattle Seahawks at Los Angeles Rams
• Projected Favorite: Rams (65.97% win probability)
• Spread: Los Angeles (-3)
• Total: 48.5 -- Over: (-112) | Under: (-108)
• Time: 4:05 p.m. ET
• Channel: FOX

Bet on Los Angeles vs. Seattle with FanDuel Sportsbook.

Cardinals vs. 49ers

The San Francisco 49ers (6-4) and the Arizona Cardinals (3-6), who both lost their last game, will play at 4:05 p.m. ET on Sunday, Nov. 16. In their previous games, the 49ers lost 42-26 to the Rams, and the Cardinals were taken down by the Seahawks 44-22.

• Game Preview: San Francisco 49ers at Arizona Cardinals
• Projected Favorite: Cardinals (52.11% win probability)
• Spread: San Francisco (-3)
• Total: 47.5 -- Over: (-115) | Under: (-105)
• Time: 4:05 p.m. ET
• Channel: FOX

Bet on Arizona vs. San Francisco with FanDuel Sportsbook.

Broncos vs. Chiefs

One of the top pass-catchers in football will be on show when Travis Kelce and the Kansas City Chiefs (5-4) visit the Denver Broncos (8-2) on Sunday, November 16, 2025.

• Game Preview: Kansas City Chiefs at Denver Broncos
• Projected Favorite: Broncos (51.87% win probability)
• Spread: Kansas City (-3.5)
• Total: 44.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Denver vs. Kansas City with FanDuel Sportsbook.

Browns vs. Ravens

The Baltimore Ravens (4-5), who grabbed a win against the Vikings in their previous tilt, visit the Cleveland Browns (2-7) at Huntington Bank Field on Nov. 16 at 4:25 p.m. ET. The Browns lost to the Jets in their last game.

• Game Preview: Baltimore Ravens at Cleveland Browns
• Projected Favorite: Ravens (69.90% win probability)
• Spread: Baltimore (-7.5)
• Total: 39.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Cleveland vs. Baltimore with FanDuel Sportsbook.

Eagles vs. Lions

The Philadelphia Eagles (7-2), who took down against the Packers in their previous contest, host the Detroit Lions (6-3) at Lincoln Financial Field on Nov. 16 at 8:20 p.m. ET. The Lions picked up the W against the Commanders in their last game.

• Game Preview: Detroit Lions at Philadelphia Eagles
• Projected Favorite: Eagles (60.12% win probability)
• Spread: Philadelphia (-2.5)
• Total: 46.5 -- Over: (-114) | Under: (-106)
• Time: 8:20 p.m. ET
• Channel: NBC/Peacock

Bet on Philadelphia vs. Detroit with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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