Missouri vs Virginia Prediction, Odds, Picks, Best Bets for Gator Bowl 2025

The Missouri Tigers versus the Virginia Cavaliers is on the college football schedule for Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding today's NCAA football betting odds.

Missouri vs Virginia Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Missouri: (-180) | Virginia: (+152)
• Spread: Missouri: -4.5 (-106) | Virginia: +4.5 (-114)
• Total: 43.5 -- Over: (-115) | Under: (-105)

Missouri vs Virginia Betting Trends

• Missouri has seven wins in 12 games against the spread this season.
• As 4.5-point favorites or more, Missouri is 5-2 against the spread.
• This season, six of Missouri's 12 games have hit the over.
• Virginia has eight wins in 13 contests against the spread this year.
• As 4.5-point underdogs or greater, Virginia is 3-0 against the spread.
• Virginia has played 13 games this year, and five of them have gone over the total.

Missouri vs Virginia Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (66.3%)

Missouri vs Virginia Point Spread

Missouri is favored by 4.5 points over Virginia. Missouri is -106 to cover the spread, with Virginia being -114.

Missouri vs Virginia Over/Under

A combined point total of 43.5 has been set for Missouri-Virginia on Dec. 27, with the over at -115 and the under at -105.

Missouri vs Virginia Moneyline

Virginia is a +152 underdog on the moneyline, while Missouri is a -180 favorite.

Missouri vs. Virginia Points Insights

Missouri vs. Virginia Game Info

• Game day: Saturday, December 27, 2025
• Game time: 7:30 p.m. ET
• TV channel: ABC
• Location: Jacksonville, Florida
• Stadium: EverBank Stadium

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Check out even more in-depth Missouri vs. Virginia analysis on FanDuel Research.